RAC3 and ANKRD11

Number of citations of the paper that reports this interaction (PubMedID 15184363)
29

Data Source:
HPRD (two hybrid, in vitro)

		RAC3	ANKRD11
Description		Rac family small GTPase 3	ankyrin repeat domain 11
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cell Cortex Endomembrane System Lamellipodium Growth Cone Cytoplasmic Vesicle Filamentous Actin Cell Projection Neuron Projection Neuronal Cell Body Intracellular Membrane-bounded Organelle Synapse Perinuclear Region Of Cytoplasm Extracellular Exosome Cell Periphery	Nucleus Nucleoplasm Cytosol Plasma Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Protein Kinase Binding Calcium-dependent Protein Binding
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Regulation Of Neuron Maturation Cerebral Cortex GABAergic Interneuron Development Cell Projection Assembly Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Neuron Projection Development Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Mediated By Integrin Intracellular Signal Transduction Homeostasis Of Number Of Cells Within A Tissue Neuromuscular Process Controlling Balance Regulation Of Small GTPase Mediated Signal Transduction Synaptic Transmission, GABAergic Positive Regulation Of Substrate Adhesion-dependent Cell Spreading	In Utero Embryonic Development Tissue Homeostasis Anatomical Structure Morphogenesis Multicellular Organism Growth Odontogenesis Of Dentin-containing Tooth Skeletal System Morphogenesis Face Morphogenesis Bone Development
Pathways		Rho GTPase cycle PCP/CE pathway
Drugs
Diseases
GWAS			Lymphocyte counts ( 27863252)
Interacting Genes		9 interacting genes: ANKRD11 AR ARHGDIA ARHGDIB CIB1 ESR1 HNF1A NRBP1 PCNT	21 interacting genes: CDCA7L CEP44 GOLGA2 HDAC3 HDAC4 HDAC5 HOOK2 HRAS IKZF1 LZTS2 MKRN3 NCOA1 NCOA2 NCOA3 PDE4DIP RAC3 SRC TFIP11 TRAF2 TRIM37 TSPOAP1
Entrez ID		5881	29123
HPRD ID		03629	12456
Ensembl ID		ENSG00000169750	ENSG00000167522
Uniprot IDs		P60763	Q6UB99
PDB IDs		2C2H 2G0N 2IC5 2OV2 2QME
Enriched GO Terms of Interacting Partners?
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