RABIF and ITGA6

Number of citations of the paper that reports this interaction (PubMedID 10094488)
14

Data Source:
BioGRID (two hybrid)

		RABIF	ITGA6
Description		RAB interacting factor	integrin subunit alpha 6
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane	Basement Membrane Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Basal Plasma Membrane Cell Surface Hemidesmosome Filopodium Integrin Alpha6-beta4 Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding	Protein Binding Insulin-like Growth Factor I Binding Neuregulin Binding Laminin Binding Protein-containing Complex Binding Cadherin Binding Metal Ion Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Protein Transport Membrane Fusion	Cell-substrate Junction Assembly Cell-matrix Adhesion Integrin-mediated Signaling Pathway Ectodermal Cell Differentiation Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Neuron Projection Development Positive Regulation Of Cell-cell Adhesion Extracellular Matrix Organization Positive Regulation Of Cell Migration Hemidesmosome Assembly Cell-substrate Adhesion Cellular Response To Extracellular Stimulus Nail Development Positive Regulation Of Phosphorylation Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Skin Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Filopodium Assembly Brown Fat Cell Differentiation Leukocyte Migration Cellular Response To Organic Cyclic Compound Cell-cell Adhesion Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			Assembly of collagen fibrils and other multimeric structures Basigin interactions Integrin cell surface interactions Integrin cell surface interactions Laminin interactions Laminin interactions Syndecan interactions Type I hemidesmosome assembly
Drugs
Diseases			Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS			Alzheimer's disease biomarkers ( 23419831) Blood protein levels ( 28240269) Diabetic kidney disease ( 26305897) Food allergy ( 29030101) Metabolite levels ( 23823483) Peanut allergy ( 29030101) Prostate cancer ( 31562322 19767753)
Interacting Genes		17 interacting genes: ITGA2 ITGA3 ITGA5 ITGA6 KYAT3 LAMTOR5 RAB10 RAB15 RAB1A RAB3A RAB8A RASSF5 REL TCF4 TERF2IP UTP14A ZNF544	22 interacting genes: ADAM9 APP BIN1 CALM1 CANX CD151 CD36 CD63 CD82 COL17A1 GIPC1 GRB2 ITGB1 ITGB4 LGALS3BP PCSK5 PLEC PRKCD PXN RABIF RPSA TSPAN4
Entrez ID		5877	3655
HPRD ID		04566	00945
Ensembl ID		ENSG00000183155	ENSG00000091409
Uniprot IDs		P47224 Q53EV1	P23229
PDB IDs		1FWQ 2FU5
Enriched GO Terms of Interacting Partners?
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