RAB5A and RABAC1

Number of citations of the paper that reports this interaction (PubMedID 10329441)
20

Data Source:
HPRD (two hybrid)

		RAB5A	RABAC1
Description		RAB5A, member RAS oncogene family	Rab acceptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Synaptic Vesicle Endosome Membrane Endomembrane System Actin Cytoskeleton Axon Dendrite Clathrin-coated Vesicle Membrane Phagocytic Vesicle Membrane Early Endosome Membrane Early Phagosome Somatodendritic Compartment Melanosome Neuronal Cell Body Terminal Bouton Axon Terminus Membrane Raft Phagocytic Vesicle Extracellular Exosome Cytoplasmic Side Of Early Endosome Membrane Postsynaptic Early Endosome Anchored Component Of Synaptic Vesicle Membrane	Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Membrane Cell Junction
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Protein Binding Protein C-terminus Binding Identical Protein Binding Proline-rich Region Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Intracellular Protein Transport Endocytosis Phagocytosis Blood Coagulation Rab Protein Signal Transduction Synaptic Vesicle Recycling Viral RNA Genome Replication Post-translational Protein Modification Early Endosome To Late Endosome Transport Positive Regulation Of Exocytosis Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Endosome Size Regulation Of Filopodium Assembly Membrane Organization Amyloid-beta Clearance By Transcytosis Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Synaptic Vesicle Exocytosis Regulation Of Autophagosome Assembly
Pathways		Synthesis of PIPs at the plasma membrane TBC/RABGAPs Clathrin-mediated endocytosis RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs Prevention of phagosomal-lysosomal fusion Factors involved in megakaryocyte development and platelet production
Drugs		L-methionine (S)-S-oxide Guanosine-5'-Triphosphate Guanosine-5'-Diphosphate
Diseases
GWAS		Heel bone mineral density ( 30598549) Iris color (L* coordinate) ( 30895295)
Interacting Genes		35 interacting genes: AGTR1 ALS2CL ANKFY1 APPL1 APPL2 CHML EEA1 GDI2 GRIK4 HTATIP2 ITSN1 NME2 OCRL RAB37 RABAC1 RABEP1 RABEP2 RABGGTB RASA1 RBSN RIN1 RIN2 RIN3 RIT2 RUFY1 SDCBP SGSM3 STX4 TBC1D15 TBC1D17 TBC1D3C TBC1D3F TRIM14 TSC2 USP6NL	65 interacting genes: CMTM3 COQ8A CREB3 DUSP12 FAM160A2 FXR2 GDI1 HRAS HRG LMNA LNX1 MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP5 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RPS20 RRAS2 S100B SGK1 SNCA SNX1 SNX10 SNX11 SNX15 SPG21 SYT16 TNIP1 TRIM32 TSHR TUBB2A TXN2 VAMP2 VIM VTA1 WIPI2 ZFYVE21
Entrez ID		5868	10567
HPRD ID		01542	05375
Ensembl ID		ENSG00000144566	ENSG00000105404
Uniprot IDs		A0A024R2K1 P20339	Q9UI14
PDB IDs		1N6H 1N6I 1N6K 1N6L 1N6N 1N6O 1N6P 1N6R 1R2Q 1TU3 1TU4 3MJH 4Q9U
Enriched GO Terms of Interacting Partners?
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