RAB1A and RABGGTA

Number of citations of the paper that reports this interaction (PubMedID 7991565)
28

Data Source:
HPRD (in vitro)

		RAB1A	RABGGTA
Description		RAB1A, member RAS oncogene family	Rab geranylgeranyltransferase subunit alpha
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cell Early Endosome Endoplasmic Reticulum Golgi Apparatus Cytosol Endomembrane System Transport Vesicle Membrane Melanosome Extracellular Exosome	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Rab-protein Geranylgeranyltransferase Complex
	Molecular Function	GTPase Activity Protein Binding GTP Binding Cadherin Binding	Rab Geranylgeranyltransferase Activity Protein Binding Zinc Ion Binding Rab GTPase Binding
	Biological Process	Autophagosome Assembly Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Endocytosis Autophagy Golgi Organization Vesicle-mediated Transport Cell Migration Virion Assembly Growth Hormone Secretion Melanosome Transport Rab Protein Signal Transduction Substrate Adhesion-dependent Cell Spreading Defense Response To Bacterium Post-translational Protein Modification Vesicle Transport Along Microtubule COPII Vesicle Coating Cilium Assembly Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Establishment Of Endothelial Intestinal Barrier Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity	Cellular Protein Modification Process Visual Perception Protein Geranylgeranylation Regulation Of Apoptotic Process Post-translational Protein Modification
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain RAB geranylgeranylation
Drugs			N-Formylmethionine FARNESYL DIPHOSPHATE Geranylgeranyl diphosphate
Diseases
GWAS
Interacting Genes		31 interacting genes: ADCK1 CAPNS1 CDKN1A CHML CREB1 CSNK1D EBP FSCN1 GOLGA2 GOLGA5 GORASP2 HIVEP1 MAPRE3 MICAL1 MICALL1 OCRL PSMD7 RABAC1 RABEP1 RABGGTA RABGGTB RABIF RFK RUSC2 SLC16A8 SNRNP27 SNRPG SYT5 TBC1D17 USO1 ZNF593	2 interacting genes: BMPR2 RAB1A
Entrez ID		5861	5875
HPRD ID		01538	03547
Ensembl ID		ENSG00000138069	ENSG00000100949
Uniprot IDs		B7Z8M7 P62820 Q5U0I6	Q92696
PDB IDs		2FOL 2WWX 3L0I 3SFV 3TKL 4FMB 4FMC 4FMD 4FME 4IRU 4JVS
Enriched GO Terms of Interacting Partners?
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