PEX5 and DDO

Number of citations of the paper that reports this interaction (PubMedID 20178365)
16

Data Source:
BioGRID (pull down, unspecified method)
HPRD (in vitro, in vivo)

		PEX5	DDO
Description		peroxisomal biogenesis factor 5	D-aspartate oxidase
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisome Peroxisomal Membrane Golgi Apparatus Cytosol Membrane Protein-containing Complex	Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	Peroxisome Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Protein Binding Enzyme Binding Small GTPase Binding Peroxisome Membrane Targeting Sequence Binding Protein N-terminus Binding	Protein Binding D-aspartate Oxidase Activity Cofactor Binding FAD Binding
	Biological Process	Protein Targeting To Peroxisome Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Docking Protein Ubiquitination Negative Regulation Of Protein Complex Assembly Protein Import Into Peroxisome Membrane	Aspartate Metabolic Process Aspartate Catabolic Process Protein Targeting To Peroxisome Insemination Grooming Behavior D-amino Acid Catabolic Process Cellular Nitrogen Compound Metabolic Process Hormone Metabolic Process Oxidation-reduction Process
Pathways		Pexophagy	Glyoxylate metabolism and glycine degradation Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		IgG glycosylation ( 23382691) Night sleep phenotypes ( 27126917)	Blood metabolite levels ( 26401656) Daytime sleep phenotypes ( 27126917) Mean platelet volume ( 27863252) Platelet count ( 27863252) Platelet distribution width ( 27863252) Systemic lupus erythematosus ( 26502338)
Interacting Genes		71 interacting genes: ACD ACOT2 ACOT4 ACOT8 ACOX2 ACOX3 AGXT AMACR ANKRD50 ATM BAAT BRCA1 CAPRIN2 CCDC14 CROT DAO DDO DECR2 DHRS4 ECI2 EP400P1 EPHX2 FIS1 GDPD5 GNPAT GSTK1 HACL1 HAO1 HAO2 HMGCL HOXA7 HSPA1A IDE IDH1 LDHB LONP2 MKRN3 MLYCD MPV17 NOS2 NUDT19 NUDT3 NUDT7 PAOX PDZK1 PEX1 PEX10 PEX12 PEX13 PEX14 PEX26 PEX6 PEX7 PIPOX POT1 PRDX5 PRR13 RPL14 S100A6 SCARB1 SCP2 SIRT3 SLC27A2 SNUPN SSTR5 TINF2 TM6SF1 TOMM7 USP2 USP9X ZNF772	2 interacting genes: COPS5 PEX5
Entrez ID		5830	8528
HPRD ID		02684	00498
Ensembl ID		ENSG00000139197	ENSG00000203797
Uniprot IDs		A0A0S2Z480 A0A0S2Z4F3 A0A0S2Z4H1 B4DR50 B4E0T2 P50542	Q99489
PDB IDs		1FCH 2C0L 2C0M 2J9Q 2W84 3R9A 4BXU 4KXK 4KYO
Enriched GO Terms of Interacting Partners?
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