PXMP2 and IMPDH2

		PXMP2	IMPDH2
Description		peroxisomal membrane protein 2	inosine monophosphate dehydrogenase 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisomal Membrane Membrane Integral Component Of Membrane Protein-containing Complex	Extracellular Region Nucleus Cytoplasm Peroxisomal Membrane Cytosol Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding	Nucleotide Binding DNA Binding RNA Binding IMP Dehydrogenase Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Biological_process	GMP Biosynthetic Process GTP Biosynthetic Process Circadian Rhythm Purine Ribonucleoside Monophosphate Biosynthetic Process Neutrophil Degranulation Lymphocyte Proliferation Oxidation-reduction Process Retina Development In Camera-type Eye Cellular Response To Interleukin-4
Pathways		Glyoxylate metabolism and glycine degradation Class I peroxisomal membrane protein import	Neutrophil degranulation Purine ribonucleoside monophosphate biosynthesis
Drugs			NADH Mycophenolate mofetil Ribavirin Mycophenolic acid Mercaptopurine Selenazole-4-Carboxyamide-Adenine Dinucleotide 6-Chloropurine Riboside, 5'-Monophosphate Inosinic Acid VX-148
Diseases
GWAS			Blood protein levels ( 28240269) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		4 interacting genes: GOLGA3 IMPDH2 KRT40 SIVA1	24 interacting genes: AKT1 ALS2 AMT ANKRD9 APIP APPL1 ATXN2 ATXN7 C1S CEACAM5 CLK1 CPLANE2 DCAF1 DNASE1L3 FBXL7 KLF7 PIAS4 PRMT1 PXMP2 PXN RAD54L2 RBM15B SUMO4 UBQLN4
Entrez ID		5827	3615
HPRD ID		10176	00895
Ensembl ID		ENSG00000176894	ENSG00000178035
Uniprot IDs		Q9NR77	A0A384N6C2 P12268
PDB IDs			1B3O 1NF7 1NFB 6I0M 6I0O
Enriched GO Terms of Interacting Partners?
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