ACTA1 and NRAP

Number of citations of the paper that reports this interaction (PubMedID 10320340)
18

Data Source:
BioGRID (pull down)

		ACTA1	NRAP
Description		actin alpha 1, skeletal muscle	nebulin related anchoring protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Extracellular Space Cytosol Striated Muscle Thin Filament Actin Filament Actin Cytoskeleton Sarcomere Lamellipodium Filopodium Cell Body Extracellular Exosome Blood Microparticle	Fascia Adherens Muscle Tendon Junction Z Disc
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Myosin Binding ADP Binding	Actin Binding Protein Binding Metal Ion Binding Actin Filament Binding Muscle Alpha-actinin Binding
	Biological Process	Muscle Contraction Response To Mechanical Stimulus Response To Extracellular Stimulus Response To Lithium Ion Positive Regulation Of Gene Expression Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Fiber Adaptation Response To Steroid Hormone Skeletal Muscle Fiber Development Cellular Response To Organonitrogen Compound Mesenchyme Migration	Biological_process Muscle Fiber Development Cardiac Muscle Thin Filament Assembly
Pathways		Striated Muscle Contraction
Drugs		Latrunculin A Sucrose Ulapualide A Kabiramide C Jaspisamide A Tmr 4-Methyl-Histidine Phosphoaminophosphonic Acid-Adenylate Ester Aplyronine A Reidispongiolide A Reidispongiolide C Sphinxolide B LATRUNCULIN B
Diseases		Congenital fiber type disproportion (CFTD) Cap myopathy Nemaline myopathy
GWAS			Heel bone mineral density ( 30598549) Plasma factor VII activating protease levels ( 30070759)
Interacting Genes		112 interacting genes: ABL1 ABRA ACTR10 ACTR1B ADSS2 AFAP1 AIF1 AJUBA AMOT ANXA2 BIN1 CCIN CCT2 CCT4 CCT5 CFL1 CLIC5 CNN1 CORO2B COTL1 CTNND1 CTTN CYFIP1 CYTH1 DHX9 DLG1 DMD DNASE1 DNMBP DTNA EGFR EPB41 EPB41L2 EPS8 FGD4 FHOD1 FSCN1 GAS2 GAS7 GC GSN HCLS1 HDAC4 HIP1R HSPB2 HTRA2 IQGAP1 ITGA2 ITPKA KIF23 KLHL20 LASP1 MACF1 MAP1A MAPT MIB2 MINPP1 MYL1 MYLK MYO10 MYO6 MYO7A MYO9B NEXN NR3C2 NRAP PAK1 PARVA PCYT1B PFDN1 PFN1 PHACTR1 PLD1 PPP1R9B PRKCA PRKCD PRKCE RAC1 RPS6KB1 S100A1 S100A4 SCIN SMTN SNCA SORBS1 SPRR1A SPTA1 SPTAN1 SPTBN2 TAGLN TJP1 TLN1 TMSB4X TMSB4Y TNNI1 TNNI3 TNNI3K TP53 TPM2 TPM3 TRIM55 TRIM63 TTN UBC USP25 USP6NL UTRN VASP VAV1 VCL VIL1 XIRP1	8 interacting genes: ACTA1 ACTB ACTN3 KLHL41 PRKAA2 TLN1 TRIM63 VCL
Entrez ID		58	4892
HPRD ID		00030	04189
Ensembl ID		ENSG00000143632	ENSG00000197893
Uniprot IDs		P68133	A0A0A0MRM2 Q86VF7
PDB IDs
Enriched GO Terms of Interacting Partners?
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