HES4 and LTN1

Number of citations of the paper that reports this interaction (PubMedID 20195357)
30

Data Source:
BioGRID (pull down)

		HES4	LTN1
Description		hes family bHLH transcription factor 4	listerin E3 ubiquitin protein ligase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Cytosol RQC Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Transcription Factor Binding Protein Dimerization Activity E-box Binding N-box Binding	Protein Binding Zinc Ion Binding Ribosomal Large Subunit Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Anterior/posterior Pattern Specification Cell Differentiation Negative Regulation Of Neuron Differentiation	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			High light scatter reticulocyte percentage of red cells ( 27863252) Hip circumference ( 28552196) Initial pursuit acceleration in psychotic disorders ( 29064472) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		5 interacting genes: COPG2 LTN1 PCBD1 PCBD2 RGS3	8 interacting genes: HES4 IRF7 STING1 TIRAP UBC UBE2D1 UBE2D2 UBE2L3
Entrez ID		57801	26046
HPRD ID		16273	10327
Ensembl ID		ENSG00000188290	ENSG00000198862
Uniprot IDs		D6REB3 E9PB28 Q9HCC6	O94822
PDB IDs			3J92
Enriched GO Terms of Interacting Partners?
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