ARRDC3 and HPGDS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ARRDC3	HPGDS
Description		arrestin domain containing 3	hematopoietic prostaglandin D synthase
Image
GO Annotations	Cellular Component	Lysosome Endosome Early Endosome Plasma Membrane	Nucleoplasm Cytoplasm Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Beta-3 Adrenergic Receptor Binding	Magnesium Ion Binding Glutathione Transferase Activity Prostaglandin-D Synthase Activity Calcium Ion Binding Protein Binding Protein Homodimerization Activity
	Biological Process	Temperature Homeostasis Negative Regulation Of Heat Generation Skin Development Positive Regulation Of Ubiquitin-protein Transferase Activity Fat Pad Development Negative Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Negative Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Cold-induced Thermogenesis	Prostaglandin Metabolic Process Glutathione Metabolic Process Signal Transduction Locomotory Behavior Cyclooxygenase Pathway Glutathione Derivative Biosynthetic Process Negative Regulation Of Male Germ Cell Proliferation
Pathways			Glutathione conjugation Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs			Glutathione Vitamin A Tretinoin 2-(2f-Benzothiazolyl)-5-Styryl-3-(4f-Phthalhydrazidyl)Tetrazolium Chloride 3-phenyl-5-(1H-pyrazol-3-yl)isoxazole PHENYL-5-(1H-PYRAZOL-3-YL)-1,3-THIAZOLE Tranilast 4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]amino}-2-hydroxybenzoic acid 4-(BENZHYDRYLOXY)-1-[3-(1H-TETRAAZOL-5-YL)PROPYL]PIPERIDINE nocodazole 3-(4-nitrophenyl)-1H-pyrazole 1-PHENYL-1H-PYRAZOLE-4-CARBOXYLIC ACID Glycerin
Diseases
GWAS		Breast cancer ( 29059683 25038754) Breast cancer (prognosis) ( 23319801) Breast cancer (survival) ( 25526632) Subcutaneous adipose tissue ( 22589738)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Blood protein levels ( 30072576 29875488) Testicular germ cell tumor ( 28604728 28604732 23666239)
Interacting Genes		14 interacting genes: ADRB2 BAG3 DCUN1D1 F2R HPGDS ITCH MAGI2 MORF4L1 OTUB2 PDCD6IP STAM2 TNFAIP3 TRIM42 UBE2E2	4 interacting genes: ABHD17A ARRDC3 HK3 MELTF
Entrez ID		57561	27306
HPRD ID		09810	04001
Ensembl ID		ENSG00000113369	ENSG00000163106
Uniprot IDs		Q96B67	A0A384P5J0 O60760
PDB IDs		4N7H 4R7V 4R7X	1IYH 1IYI 1V40 2CVD 2VCQ 2VCW 2VCX 2VCZ 2VD0 2VD1 3EE2 3KXO 3VI5 3VI7 4EC0 4EDY 4EDZ 4EE0 5AIS 5AIV 5AIX 5YWE 5YWX 5YX1 6N4E
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?