PTK2 and CSK

  • Number of citations of the paper that reports this interaction (PubMedID 7529872)
  • 30
  • Data Source:
  • HPRD (in vitro, in vivo)

PTK2

CSK

Description protein tyrosine kinase 2 C-terminal Src kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acute graft versus host disease in bone marrow transplantation (recipient effect) ( 27595289)
  • Atrial fibrillation ( 30061737 29892015)
  • Diastolic blood pressure ( 30224653)
  • Mean corpuscular hemoglobin ( 27863252)
  • Mood instability ( 31168069)
  • Nickel levels ( 26025379)
  • Response to interferon beta therapy ( 21502966)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Blood pressure ( 21909110)
  • Blood protein levels ( 30072576)
  • Caffeine consumption ( 21490707)
  • Diastolic blood pressure ( 26390057 19430479 19430483)
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Hypertension ( 31513605)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Mean arterial pressure ( 27618448)
  • Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Medication use (agents acting on the renin-angiotensin system) ( 31015401)
  • Medication use (beta blocking agents) ( 31015401)
  • Medication use (diuretics) ( 31015401)
  • Offspring birth weight ( 31043758)
  • Serum albumin level ( 29403010)
  • Systemic lupus erythematosus ( 27399966 26502338 28714469)
  • Systemic lupus erythematosus and Systemic sclerosis ( 23740937)
  • Systemic sclerosis ( 31672989)
  • Systolic blood pressure ( 30578418)
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858)
  • Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
Interacting Genes 112 interacting genes: ACTN1 APP ARHGAP26 ASAP1 ATG12 BBS10 BCAR1 BIN1 BMX CCR5 CD47 CD79B CIB1 CRK CSK CSPG4 CXCR4 DCC DDX39A DEF6 DLGAP3 DNM2 DOK4 EEF1G EFS EGFR EPHA2 EPHB2 EPS8L2 ERBB2 ERBB3 EZR F13A1 FBP1 FGR FLT1 FLT4 FYN GIT1 GRB2 GRB7 GSK3B GZMB HES1 IGHM INSR IRS1 ITGAV ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 JAK2 KCNMA1 LCK LPXN LYN MAPK8IP3 MDM2 MICAL1 NACAD NASP NCK1 NCK2 NEDD8 NEDD9 NEO1 PDGFRB PIAS1 PIK3R1 PKD1 PLCG1 PPP1CB PTEN PTK2B PTPN11 PTPN12 PTPRH PXN RAC1 RB1CC1 RET RIPK1 ROCK1 SAE1 SELE SH2D1A SH2D1B SHC1 SOCS1 SOCS2 SOCS3 SORBS1 SRC SRPK1 STAT1 SYK TGFB1I1 TLN1 TNFRSF1A TNS1 TNS3 TP53 TRIM15 TRIO TRIP6 TSC2 VCL YES1 ZFYVE21 ZNF331 50 interacting genes: ADRB2 ARRB1 CAV1 CD247 CD3E CD44 CDC45 CDH5 CREBBP DAB2 DOK1 DOK2 DOK3 ETFA FGR FHL2 FYN G3BP1 GJA1 GSN HCK HNRNPK ID3 IGF1R INSR KHDRBS1 LAIR1 LCK LYN MAPK15 PAG1 PDPK1 PECAM1 PLD2 PRKACA PTK2 PTPN12 PTPN18 PTPN22 PXN RASA1 RGS16 SDC3 SHC1 SIT1 SRC TGFB1I1 TLR3 ZAP70 ZNF212
Entrez ID 5747 1445
HPRD ID 02859 00496
Ensembl ID ENSG00000169398 ENSG00000103653
Uniprot IDs Q05397 Q59GM6 Q59GN8 Q658W2 A8K3B6 B2R6Q4 P41240
PDB IDs 1K04 1K05 1MP8 1OW6 1OW7 1OW8 2ETM 2IJM 3B71 3BZ3 3PXK 3S9O 4EBV 4EBW 4GU6 4GU9 4I4E 4I4F 4K8A 4K9Y 4KAB 4KAO 4NY0 4Q9S 6I8Z 1BYG 1CSK 3D7T 3D7U 3EAC 3EAZ
Enriched GO Terms of Interacting Partners?
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