PTBP1 and HNRNPAB

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		PTBP1	HNRNPAB
Description		polypyrimidine tract binding protein 1	heterogeneous nuclear ribonucleoprotein A/B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm RNA Polymerase II Transcription Factor Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Poly-pyrimidine Tract Binding Pre-mRNA Binding	DNA-binding Transcription Factor Activity RNA Binding MRNA Binding Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of Translation RNA Splicing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Negative Regulation Of RNA Splicing Positive Regulation Of Protein Dephosphorylation Regulation Of RNA Splicing Regulation Of Cell Differentiation Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Muscle Cell Differentiation Positive Regulation Of Calcineurin-NFAT Signaling Cascade IRES-dependent Viral Translational Initiation	Epithelial To Mesenchymal Transition Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process
Pathways		FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Blood protein levels ( 30072576)
Interacting Genes		28 interacting genes: APBB1 APP CALCOCO2 CASP3 FUS H3-4 HIF1A HMGA1 HMGA2 HNRNPAB HNRNPL IL7R LINC00839 MARK4 NONO PCBP1 PCBP2 PCBP3 PRKACA QKI RAVER1 RAVER2 RBFOX2 RBM10 SFPQ SNRPA SRPK2 ZMYM2	17 interacting genes: ACTB DEDD2 ELAVL2 ERG H3-4 H3C1 HMGA1 HOXC13 HOXD4 IL7R POLR3D PTBP1 PTBP2 RBFOX2 TP63 USP19 YWHAG
Entrez ID		5725	3182
HPRD ID		02823	04067
Ensembl ID		ENSG00000011304	ENSG00000197451
Uniprot IDs		P26599	Q99729
PDB IDs		1QM9 1SJQ 1SJR 2AD9 2ADB 2ADC 2EVZ 2N3O 3ZZY 3ZZZ	3S7R
Enriched GO Terms of Interacting Partners?
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