PMEPA1 and DCTN6

Number of citations of the paper that reports this interaction (PubMedID 28218281)
1

		PMEPA1	DCTN6
Description		prostate transmembrane protein, androgen induced 1	dynactin subunit 6
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Plasma Membrane Endosome Membrane Integral Component Of Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle	Condensed Chromosome Kinetochore Centrosome Cytosol Dynactin Complex
	Molecular Function	Protein Binding WW Domain Binding R-SMAD Binding
	Biological Process	Negative Regulation Of SMAD Protein Complex Assembly Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Androgen Receptor Signaling Pathway Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation	ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		Downregulation of TGF-beta receptor signaling	MHC class II antigen presentation HSP90 chaperone cycle for steroid hormone receptors (SHR) COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Response to fenofibrate (adiponectin levels) ( 23149075)	Breast size ( 27182965)
Interacting Genes		6 interacting genes: DCTN5 DCTN6 HGS NEDD4 STAM UBQLN4	8 interacting genes: APP CDK1 ERRFI1 HSPB2 NCOA3 PMEPA1 RPSA UBXN8
Entrez ID		56937	10671
HPRD ID		09415	09907
Ensembl ID		ENSG00000124225	ENSG00000104671
Uniprot IDs		Q5JY37 Q969W9	O00399
PDB IDs			3TV0
Enriched GO Terms of Interacting Partners?
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