LXN and TRIM39

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LXN	TRIM39
Description		latexin	tripartite motif containing 39
Image
GO Annotations	Cellular Component	Extracellular Space Cytoplasm	Nucleus Mitochondrion Cytosol
	Molecular Function	Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding	Protein Binding Zinc Ion Binding Transferase Activity Identical Protein Binding
	Biological Process	Inflammatory Response Negative Regulation Of Endopeptidase Activity Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain	Apoptotic Process Mitotic G2 DNA Damage Checkpoint Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Protein Stabilization Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Apoptotic Signaling Pathway
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)	Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Cutaneous lupus erythematosus ( 25827949) Neuroticism ( 29255261)
Interacting Genes		6 interacting genes: DPYD GSG1L MAGEA8 TMEM14A TRIM39 ZKSCAN4	55 interacting genes: APP CACTIN CCNC DCUN1D1 DCX DIP2A EIF4A2 EPHB6 HINFP KDM1A LMNA LNX1 LXN MED18 MNAT1 OTUB2 OTUD6A PDLIM5 PLCD4 POLI PRPF3 PSMA6 PSMD9 RECK RNF166 SMCO3 TP53 TRIM17 TRIM21 TRIM8 TTC32 UBAC1 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBTD1 UBTD2 UBXN1 UBXN6 USP2 USP39 USP5 WDFY3 ZKSCAN4 ZNF26
Entrez ID		56925	56658
HPRD ID		14327	09298
Ensembl ID		ENSG00000079257	ENSG00000204599
Uniprot IDs		Q9BS40	A0A024RCP5 A0A024RCR1 Q9HCM9
PDB IDs		2BO9	2DID 2DIF 2ECJ
Enriched GO Terms of Interacting Partners?
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