KIZ and TACC3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KIZ	TACC3
Description		kizuna centrosomal protein	transforming acidic coiled-coil containing protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cell Projection	Spindle Pole Cytoplasm Cytosol Centriolar Satellite Intracellular Membrane-bounded Organelle Mitotic Spindle
	Molecular Function	Protein Binding Protein Kinase Binding	Protein Binding
	Biological Process	Spindle Organization	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Metaphase/anaphase Transition Of Mitotic Cell Cycle Cell Proliferation Cerebral Cortex Development Cell Division Regulation Of Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis
Pathways			NOTCH3 Activation and Transmission of Signal to the Nucleus Negative regulation of NOTCH4 signaling
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder ( 30804558) Height ( 31562340)	Bladder cancer ( 24163127 20972438) Urinary bladder cancer ( 20348956)
Interacting Genes		3 interacting genes: AAR2 MEOX2 TACC3	16 interacting genes: AKAP9 ARNT ARNT2 ASPSCR1 AURKA CIB3 CLIP4 EIF3C KAT2A KIZ NDEL1 NOD2 SNX20 TBC1D22B TTF2 VPS37C
Entrez ID		55857	10460
HPRD ID		12760	05601
Ensembl ID		ENSG00000088970	ENSG00000013810
Uniprot IDs		A0A087X251 Q2M2Z5	Q9Y6A5
PDB IDs			5LXN 5LXO 5ODS 5ODT
Enriched GO Terms of Interacting Partners?
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