PRKAR1B and AKAP1

Number of citations of the paper that reports this interaction (PubMedID 12634056)
4

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		PRKAR1B	AKAP1
Description		protein kinase cAMP-dependent type I regulatory subunit beta	A-kinase anchoring protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane CAMP-dependent Protein Kinase Complex Ciliary Base Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse	Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane Integral Component Of Membrane
	Molecular Function	CAMP-dependent Protein Kinase Inhibitor Activity Protein Binding CAMP-dependent Protein Kinase Regulator Activity CAMP Binding Protein Kinase A Catalytic Subunit Binding 3',5'-cyclic-GMP Phosphodiesterase Activity	RNA Binding Protein Binding Protein Kinase A Regulatory Subunit Binding
	Biological Process	Renal Water Homeostasis Protein Phosphorylation Blood Coagulation Learning Or Memory CGMP-mediated Signaling Activation Of Protein Kinase A Activity Modulation Of Chemical Synaptic Transmission Cellular Response To Glucagon Stimulus Regulation Of Synaptic Vesicle Cycle Negative Regulation Of CAMP-dependent Protein Kinase Activity	Blood Coagulation Regulation Of Protein Kinase A Signaling
Pathways		PKA activation PKA activation in glucagon signalling DARPP-32 events Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins CREB1 phosphorylation through the activation of Adenylate Cyclase Hedgehog 'off' state ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production	Mitochondrial calcium ion transport Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Plasma free amino acid levels ( 30659259) Red blood cell count ( 27863252)	Blond vs. brown/black hair color ( 30531825) Crohn's disease ( 26192919) Freckles ( 29895819) Inflammatory bowel disease ( 26192919) Male-pattern baldness ( 27182965)
Interacting Genes		8 interacting genes: AKAP1 EGFR PPP1R9A PRKAR1A SMAD3 SMAD4 WNK1 WRN	12 interacting genes: AMY1A APP CAV1 CFAP91 MYCBP PPP1CA PRKACA PRKAR1A PRKAR1B PRKAR2A PRKAR2B PTPN21
Entrez ID		5575	8165
HPRD ID		01485	03905
Ensembl ID		ENSG00000188191	ENSG00000121057
Uniprot IDs		P31321	A0A140VK05 B4DN86 Q92667
PDB IDs		4DIN 4F9K
Enriched GO Terms of Interacting Partners?
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