NHP2 and MYL2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		NHP2	MYL2
Description		NHP2 ribonucleoprotein	myosin light chain 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nucleoplasm Telomerase Holoenzyme Complex Small Nucleolar Ribonucleoprotein Complex Box H/ACA SnoRNP Complex Box H/ACA ScaRNP Complex Box H/ACA Telomerase RNP Complex	Cytosol Cytoskeleton Actin Cytoskeleton Myosin Complex Myofibril Sarcomere A Band Cardiac Myofibril
	Molecular Function	RNA Binding Protein Binding Box H/ACA SnoRNA Binding Telomerase RNA Binding	Actin Monomer Binding Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding
	Biological Process	Cleavage Involved In RRNA Processing Maturation Of LSU-rRNA Telomere Maintenance Via Telomerase RRNA Pseudouridine Synthesis SnRNA Pseudouridine Synthesis Positive Regulation Of Telomerase RNA Localization To Cajal Body	Regulation Of The Force Of Heart Contraction Regulation Of Striated Muscle Contraction Heart Development Post-embryonic Development Muscle Filament Sliding Negative Regulation Of Cell Growth Muscle Cell Fate Specification Muscle Fiber Development Cardiac Myofibril Assembly Ventricular Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Positive Regulation Of The Force Of Heart Contraction
Pathways		Telomere Extension By Telomerase rRNA modification in the nucleus and cytosol	Striated Muscle Contraction
Drugs
Diseases		Dyskeratosis congenita (DC), including: X-linked dyskeratosis congenita (DKCX); Autosomal dominant dyskeratosis congenita (DKCA1); Autosomal recessive dyskeratosis congenita (DKCB1)	Hypertrophic cardiomyopathy (HCM)
GWAS		Platelet count ( 29403010)	Alcohol consumption ( 21270382) Alcohol consumption (drinkers vs non-drinkers) ( 28485404) Alcohol consumption (max-drinks) ( 29460428) Body mass index ( 24861553) Coffee consumption ( 29367735) Coronary heart disease ( 23364394) Drinking behavior ( 23364009) Gamma glutamyl transpeptidase ( 21909109) Glycemic traits ( 23575436) Gout ( 25646370) HDL cholesterol ( 21909109) HDL cholesterol levels ( 28334899) High density lipoprotein cholesterol levels ( 30718733) Metabolic syndrome ( 25705158) Metabolic syndrome (multivariate analysis) ( 29632305) Neutrophil count ( 29403010) Urate levels ( 31578528) White blood cell count ( 29403010)
Interacting Genes		9 interacting genes: IKBKG JMJD6 MYL2 NEDD4 NEDD4L NOP10 NOS1AP PRNP UTP23	11 interacting genes: CDC42BPA GJB5 LRSAM1 MYOC NHP2 PAK2 PKM PPP1R12C TRIM63 USP6 ZNF529
Entrez ID		55651	4633
HPRD ID		07570	01181
Ensembl ID		ENSG00000145912	ENSG00000111245
Uniprot IDs		J3QSY4 Q9NX24	P10916 Q6IB42
PDB IDs			5TBY
Enriched GO Terms of Interacting Partners?
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