PPP4C and CCDC6

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		PPP4C	CCDC6
Description		protein phosphatase 4 catalytic subunit	coiled-coil domain containing 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Microtubule Organizing Center Cytosol Plasma Membrane Protein Phosphatase 4 Complex	Cytosol Cytoskeleton
	Molecular Function	NF-kappaB-inducing Kinase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Metal Ion Binding	Structural Constituent Of Cytoskeleton Protein Binding SH3 Domain Binding
	Biological Process	Protein Dephosphorylation Regulation Of Double-strand Break Repair Via Homologous Recombination NIK/NF-kappaB Signaling	Cytoskeleton Organization Biological_process
Pathways		Processing of DNA double-strand break ends
Drugs
Diseases			Thyroid cancer
GWAS		Adventurousness ( 30643258) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Mean corpuscular volume ( 29403010) Medication use (diuretics) ( 31015401) Schizophrenia ( 25056061 29483656)	Alopecia areata ( 25608926) Heel bone mineral density ( 30598549) Metabolite levels ( 23823483) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		21 interacting genes: CCDC6 DHX38 HDAC3 IGBP1 JUN NFKB1 PPP2R1A PPP2R5D PPP4R1 PPP4R2 PPP4R3B PPP4R4 REL RELA RPA2 TIPRL TK1 TMSB4X TP53 TRAF6 TRIM28	7 interacting genes: ATF2 CREB1 CSNK2A1 FBXW7 MAPK3 PPP4C UBE2I
Entrez ID		5531	8030
HPRD ID		03615	09064
Ensembl ID		ENSG00000149923	ENSG00000108091
Uniprot IDs		A0A024R625 P60510	Q05CP8 Q16204
PDB IDs
Enriched GO Terms of Interacting Partners?
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