PPP2R5E and BHLHB9

Number of citations of the paper that reports this interaction (PubMedID 15034937)
7

Data Source:
HPRD (two hybrid)

		PPP2R5E	BHLHB9
Description		protein phosphatase 2 regulatory subunit B'epsilon	basic helix-loop-helix family member b9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Protein Phosphatase Type 2A Complex Nucleus Cytoplasm Cytosol	Nucleoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Protein Phosphatase Regulator Activity Protein Phosphatase Activator Activity	Protein Homodimerization Activity
	Biological Process	Protein Dephosphorylation Signal Transduction Regulation Of Protein Autophosphorylation Regulation Of Phosphoprotein Phosphatase Activity	Learning Or Memory Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Neurogenesis Positive Regulation Of Synapse Assembly Positive Regulation Of Dendritic Spine Morphogenesis
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion CTLA4 inhibitory signaling Platelet sensitization by LDL Disassembly of the destruction complex and recruitment of AXIN to the membrane Disassembly of the destruction complex and recruitment of AXIN to the membrane Misspliced GSK3beta mutants stabilize beta-catenin S33 mutants of beta-catenin aren't phosphorylated S37 mutants of beta-catenin aren't phosphorylated S45 mutants of beta-catenin aren't phosphorylated T41 mutants of beta-catenin aren't phosphorylated APC truncation mutants have impaired AXIN binding AXIN missense mutants destabilize the destruction complex Truncations of AMER1 destabilize the destruction complex RHO GTPases Activate Formins RAF activation Negative regulation of MAPK pathway PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Response to antineoplastic agents ( 21659360) Systolic blood pressure ( 28135244)
Interacting Genes		18 interacting genes: APP BHLHB9 BHLHE41 CHEK2 CLOCK CRY1 CRY2 CSNK1E CSNK2B DELEC1 FBXW11 PPP1CA PPP2CA PPP2R1B RACGAP1 RORC SGO1 SMAD9	3 interacting genes: APP IPO5 PPP2R5E
Entrez ID		5529	80823
HPRD ID		09040	10028
Ensembl ID		ENSG00000154001	ENSG00000198908
Uniprot IDs		Q16537	Q6PI77
PDB IDs
Enriched GO Terms of Interacting Partners?
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