ATG16L1 and ATG12

Number of citations of the paper that reports this interaction (PubMedID 30778222)
7

Data Source:
BioGRID (biochemical, pull down)

		ATG16L1	ATG12
Description		autophagy related 16 like 1	autophagy related 12
Image
GO Annotations	Cellular Component	Autophagosome Membrane Autophagosome Cytosol Axoneme Phagophore Assembly Site Membrane	Autophagosome Cytosol Phagocytic Vesicle Membrane Phagophore Assembly Site Membrane Atg12-Atg5-Atg16 Complex
	Molecular Function	Protein Binding Ubiquitin-like Protein Transferase Activity Identical Protein Binding GTPase Binding	Protein Binding
	Biological Process	Autophagosome Assembly Protein Transport Macroautophagy Negative Stranded Viral RNA Replication	Autophagosome Assembly Autophagy Of Mitochondrion C-terminal Protein Lipidation Viral Process Macroautophagy Autophagy Of Nucleus
Pathways		Macroautophagy Macroautophagy	Macroautophagy Macroautophagy Pink/Parkin Mediated Mitophagy Receptor Mediated Mitophagy Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases		Crohn's disease
GWAS		Bilirubin levels ( 31319653) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 28067908 20570966 22936669 22412388 17435756 17554300 21102463 23128233) Inflammatory bowel disease ( 28067908) Pediatric autoimmune diseases ( 26301688)
Interacting Genes		16 interacting genes: APP ATG12 ATG5 C3 CSNK2A1 CSNK2A2 GAN GIGYF2 NOD1 OPTN PLD3 RAB33A RAB33B SCAP TMEM59 UBC	12 interacting genes: APP ATG10 ATG16L1 ATG3 ATG5 ATG7 CRX KRTAP4-12 MDFI PLSCR1 PTK2 SRP19
Entrez ID		55054	9140
HPRD ID		16498	08496
Ensembl ID		ENSG00000085978	ENSG00000145782
Uniprot IDs		A0A024R494 A0A024R4B6 Q17RG0 Q53SV2 Q676U5	O94817
PDB IDs		4GDK 4GDL 4NAW 4TQ0 5D7G 5NPV 5NPW 5NUV 5ZYX	4GDK 4GDL 4NAW
Enriched GO Terms of Interacting Partners?
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