AURKAIP1 and AJUBA

Number of citations of the paper that reports this interaction (PubMedID 13678582)
206

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		AURKAIP1	AJUBA
Description		aurora kinase A interacting protein 1	ajuba LIM protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Ribosome Intracellular Membrane-bounded Organelle	P-body Nucleus Nucleoplasm Transcription Factor Complex Golgi Apparatus Microtubule Organizing Center Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Focal Adhesion Lamellipodium
	Molecular Function	Protein Binding	Chromatin Binding Transcription Corepressor Activity Protein Binding Alpha-catenin Binding Metal Ion Binding Actin Filament Binding
	Biological Process	MRNA Processing Negative Regulation Of Mitotic Nuclear Division Positive Regulation Of Proteolysis Mitochondrial Translational Elongation Mitochondrial Translational Termination	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Response To Hypoxia Regulation Of Transcription, DNA-templated Cytoskeleton Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Lamellipodium Assembly Regulation Of Cell Migration Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Protein Complex Assembly Negative Regulation Of Kinase Activity Cellular Protein Localization Gene Silencing By MiRNA Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Hippo Signaling Regulation Of GTPase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAP Kinase Activity Glycerophospholipid Biosynthetic Process Focal Adhesion Assembly Regulation Of Cellular Response To Hypoxia Positive Regulation Of Gene Silencing By MiRNA
Pathways		Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination	Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Regulation of PLK1 Activity at G2/M Transition Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Inflammatory bowel disease ( 28067908) Intraocular pressure ( 29617998) Ulcerative colitis ( 28067908)	Insular cortex volume ( 31530798) Macular thickness ( 30535121) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Spatial processing ( 31596458)
Interacting Genes		3 interacting genes: AJUBA AURKA FAM9B	10 interacting genes: ACTA1 AURKAIP1 AURKB BCAR1 CTNNA1 GFI1B GRB2 LATS2 LCK SLC1A2
Entrez ID		54998	84962
HPRD ID		16457	16426
Ensembl ID		ENSG00000175756	ENSG00000129474
Uniprot IDs		Q9NWT8	Q96IF1
PDB IDs		3J9M 6NU2 6NU3
Enriched GO Terms of Interacting Partners?
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