TESC and CCDC91

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TESC	CCDC91
Description		tescalcin	coiled-coil domain containing 91
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Lamellipodium Ruffle Membrane	Nucleoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane
	Molecular Function	Magnesium Ion Binding Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Phosphatase Inhibitor Activity Protein Homodimerization Activity	Identical Protein Binding
	Biological Process	Negative Regulation Of Protein Kinase Activity Negative Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Protein Transport Cell Differentiation Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Sodium:proton Antiporter Activity Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription, DNA-templated Protein Stabilization Protein Maturation Cellular Response To Retinoic Acid Protein Localization To Plasma Membrane	Protein Transport Golgi To Lysosome Transport
Pathways
Drugs
Diseases
GWAS		Dentate gyrus granule cell layer volume ( 30279459) Dentate gyrus molecular layer volume ( 30279459) Hippocampal subfield CA1 volume ( 30279459) Hippocampal subfield CA4 volume ( 30279459) Hippocampal tail volume ( 30279459) Mean platelet volume ( 27863252) Total hippocampal volume ( 30279459)	Adverse response to drug ( 30420678) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Bone ultrasound measurement (velocity of sound) ( 28472463) Breast size ( 27182965) Chronic obstructive pulmonary disease ( 30804561) FEV1 ( 30804560) Heel bone mineral density ( 30598549) Height ( 28552196 20881960 25282103 23563607 31562340) Hip circumference adjusted for BMI ( 25673412) Lumbar spine bone mineral density (trabecular) ( 27476799) Lung function (FEV1) ( 28166213 26635082) Lung function (FVC) ( 28166213 26635082 30804560) Lung function (low FEV1 vs high FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Narrowest width of the femoral neck ( 30888730) Obesity-related traits ( 23251661) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Osteoarthritis of the hand ( 28855172) Peak expiratory flow ( 30804560) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes		7 interacting genes: CCDC91 DYNLT3 HMG20A RAI1 RPL36 SLC9A1 WBP11	6 interacting genes: ECT2 EWSR1 GGA1 GGA2 SYNRG TESC
Entrez ID		54997	55297
HPRD ID		11649	16905
Ensembl ID		ENSG00000088992	ENSG00000123106
Uniprot IDs		Q96BS2	A0A024RAW6 Q05D28 Q7Z6B0
PDB IDs			1OM9
Enriched GO Terms of Interacting Partners?
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