GATAD2A and PAK4

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		GATAD2A	PAK4
Description		GATA zinc finger domain containing 2A	p21 (RAC1) activated kinase 4
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm NuRD Complex Nuclear Speck	Cytoplasm Golgi Apparatus Adherens Junction Focal Adhesion
	Molecular Function	Protein Binding Zinc Ion Binding Protein Binding, Bridging Sequence-specific DNA Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Cadherin Binding Involved In Cell-cell Adhesion
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation Negative Regulation Of Transcription, DNA-templated	Regulation Of Cell Growth Apoptotic Process Cytoskeleton Organization Cell Cycle Signal Transduction Regulation Of Mitotic Cell Cycle Cell Migration Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Positive Regulation Of Angiogenesis Dendritic Spine Development Cellular Response To Organic Cyclic Compound Cell-cell Adhesion Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways		HDACs deacetylate histones ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression Regulation of TP53 Activity through Acetylation RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription	Activation of RAC1
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Bipolar II disorder ( 31043756) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Breast cancer ( 29059683) Height ( 25282103 31562340) Nonalcoholic fatty liver disease ( 29385134) Pulse pressure ( 30578418) Red cell distribution width ( 28957414) Response to fenofibrate (LDL cholesterol levels) ( 27002377) Schizophrenia ( 25056061 29483656 23974872) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Strenuous sports or other exercises ( 29899525) Type 2 diabetes ( 28869590)
Interacting Genes		11 interacting genes: CREBBP H2AC20 H2BC21 H3C1 H4C1 KAT2B KRT40 MBD2 MBD3 PAK4 SPOP	24 interacting genes: APP CDC42 DGCR6L DLST FBXO25 FGFR2 G6PD GATAD2A GRB2 H1-1 ITGAV ITGB5 LIMK1 POT1 PPARG RAN RHOU SH3RF2 SRPK1 SRPK2 TERF1 YWHAG YWHAQ YWHAZ
Entrez ID		54815	10298
HPRD ID		11741	05675
Ensembl ID		ENSG00000167491	ENSG00000130669
Uniprot IDs		A0A024R7K7 A0A024R7M6 Q86YP4	A0A024R0J1 A0A024R0L8 O96013
PDB IDs		2L2L	2BVA 2CDZ 2J0I 2OV2 2Q0N 2X4Z 4APP 4FIE 4FIF 4FIG 4FIH 4FII 4FIJ 4JDH 4JDI 4JDJ 4JDK 4L67 4NJD 4O0V 4O0X 4O0Y 4XBR 4XBU 5BMS 5I0B 5UPK 5UPL 5VED 5VEE 5VEF 5XVA 5XVF 5XVG 5ZJW
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?