MBTD1 and EPC1

Number of citations of the paper that reports this interaction (PubMedID 27153538)
57

Data Source:
BioGRID (affinity chromatography technology, pull down)

		MBTD1	EPC1
Description		mbt domain containing 1	enhancer of polycomb homolog 1
Image
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Nuclear Body Nuclear Membrane Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	Protein Binding Zinc Ion Binding Methylated Histone Binding	Histone Acetyltransferase Activity Protein Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Embryonic Skeletal System Development	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Vascular Smooth Muscle Cell Differentiation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G0 To G1 Transition
Pathways			HATs acetylate histones Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Diastolic blood pressure ( 30224653) Metabolite levels ( 23823483) Platelet distribution width ( 27863252) Sexual dysfunction (female) ( 22509378)
Interacting Genes		2 interacting genes: EPC1 H4C1	6 interacting genes: E2F6 HOPX KRT15 MBTD1 RINT1 TRIM27
Entrez ID		54799	80314
HPRD ID		14369	09941
Ensembl ID		ENSG00000011258	ENSG00000120616
Uniprot IDs		Q05BQ5	Q9H2F5
PDB IDs		3FEO 4C5I 6NFX	6NFX
Enriched GO Terms of Interacting Partners?
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