NECAB2 and NIP7

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NECAB2	NIP7
Description		N-terminal EF-hand calcium binding protein 2	nucleolar pre-rRNA processing protein NIP7
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Axon Dendrite	Nucleoplasm Nucleolus Cytosol Preribosome, Large Subunit Precursor
	Molecular Function	Calcium Ion Binding Protein Binding A2A Adenosine Receptor Binding Type 5 Metabotropic Glutamate Receptor Binding	RNA Binding Protein Binding
	Biological Process	Regulation Of Amyloid Precursor Protein Biosynthetic Process Positive Regulation Of Adenosine Receptor Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Internalization Positive Regulation Of Protein Localization To Membrane	Ribosome Assembly Ribosomal Large Subunit Biogenesis
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Body mass index (change over time) ( 25378290) Corneal astigmatism ( 29422769) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Rheumatoid arthritis ( 30891314)	Body mass index ( 26426971) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		63 interacting genes: ADORA2A AIMP2 BEX2 BEX3 BYSL C1orf109 CAPN3 CARD9 CCDC121 CCDC146 CCDC151 CCDC153 CCDC33 CCNK CENPO CPEB2 DAXX DFFA DGCR6 DGCR6L EAF2 EHHADH EIF4E2 EMILIN1 FAM161A FANCG FXR2 GCC1 GOLGA2 GTPBP10 HAUS1 INPP1 ISCU KANSL1 KDM1A KIFC3 KLC3 KLC4 KPNA2 LENG1 LNX1 MED14 MRPS27 NEK6 NIP7 NOC4L NTAQ1 PCM1 POLR2C PRKAA2 PSMA1 RCOR3 RIC8A RUNX1T1 SDCBP SH2D4A SSC5D TEX11 TTC25 TTR USHBP1 USP7 VTA1	5 interacting genes: CRX LZTS2 NECAB2 NOL8 ZBED1
Entrez ID		54550	51388
HPRD ID		13263	16709
Ensembl ID		ENSG00000103154	ENSG00000132603
Uniprot IDs		Q7Z6G3	Q9Y221
PDB IDs			1SQW 1T5Y
Enriched GO Terms of Interacting Partners?
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