POU2F2 and NR2F1

Number of citations of the paper that reports this interaction (PubMedID 8622679)
22

Data Source:
BioGRID (pull down)

		POU2F2	NR2F1
Description		POU class 2 homeobox 2	nuclear receptor subfamily 2 group F member 1
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle	Nucleus Nucleoplasm Cytosol
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Domain Specific Binding Sequence-specific DNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Transcription Coactivator Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Retinoic Acid-responsive Element Binding
	Biological Process	Mature B Cell Differentiation Immunoglobulin Secretion Involved In Immune Response Transcription By RNA Polymerase II Humoral Immune Response Cell Differentiation SnRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Cell Maturation	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Negative Regulation Of Neuron Projection Development Cell Differentiation Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes	Nuclear Receptor transcription pathway
Drugs			beta-Naphthoflavone
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Chronotype ( 30696823) Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016)
Interacting Genes		14 interacting genes: AR ESR1 GAPDH HMGA1 HMGB2 MNAT1 NR2F1 NR3C1 PGR POU2AF1 RXRA TBP TXNRD1 XRCC6	23 interacting genes: AHR BCL11A BCL11B CBX5 COPS2 EEF1D ESR1 GTF2B HNF4A ISL1 MAP6 MCPH1 NCOA1 NCOA2 NCOA3 NCOR2 NSD1 PFDN1 PHB2 POU2F2 RXRA SP1 THRA
Entrez ID		5452	7025
HPRD ID		01251	00584
Ensembl ID		ENSG00000028277	ENSG00000175745
Uniprot IDs		B5ME60 H0YLL6 P09086	P10589
PDB IDs		1HDP	2EBL
Enriched GO Terms of Interacting Partners?
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