ZFAND6 and TRAF5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZFAND6	TRAF5
Description		zinc finger AN1-type containing 6	TNF receptor associated factor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Centrosome Cytosol Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex Plasma Membrane Receptor Complex
	Molecular Function	Molecular_function DNA Binding Protein Binding Zinc Ion Binding Polyubiquitin Modification-dependent Protein Binding	Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Thioesterase Binding Identical Protein Binding
	Biological Process	Protein Targeting To Peroxisome Apoptotic Process Negative Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Response To Tumor Necrosis Factor	Apoptotic Process Signal Transduction Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of JNK Cascade Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein K63-linked Ubiquitination
Pathways		Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases
GWAS		Eosinophil counts ( 29403010) Monocyte count ( 29403010) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Type 2 diabetes ( 20581827) White blood cell count ( 29403010)	Household income (MTAG) ( 31844048)
Interacting Genes		6 interacting genes: CDC34 DNM2 PKN1 TRAF2 TRAF5 UBC	45 interacting genes: BEX3 CAPNS1 CCDC184 CD27 CD40 COG7 COMMD3 DGKH ENOX2 GOLGA2 GORASP2 HSD17B10 LTBR MAP3K14 MAP3K5 MDM2 NMI NUMBL RAD23A RIPK1 RIPK2 RNF111 SDCBP SEC13 SERPINB9 TBK1 TDP2 THAP1 TNFRSF11A TNFRSF12A TNFRSF13B TNFRSF14 TNFRSF19 TNFRSF4 TNFRSF8 TRAF2 TRAF3 TRAF3IP2 TRAF6 TRIM27 TRIM37 TRIM8 UBC USP7 ZFAND6
Entrez ID		54469	7188
HPRD ID		18314	03834
Ensembl ID		ENSG00000086666	ENSG00000082512
Uniprot IDs		Q6FIF0	O00463
PDB IDs
Enriched GO Terms of Interacting Partners?
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