XRN1 and CTSB

  • Number of citations of the paper that reports this interaction (PubMedID 15231747)
  • 56
  • Data Source:
  • BioGRID (two hybrid)

XRN1

CTSB

Description 5'-3' exoribonuclease 1 cathepsin B
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488 28240269)
  • C-reactive protein levels or triglyceride levels (pleiotropy) ( 27286809)
  • Dental caries (decayed, missing and filled teeth) ( 31533690)
  • General risk tolerance (MTAG) ( 30643258)
  • Leprosy ( 27976721)
  • Parkinson's disease ( 28892059)
  • Parkinson's disease in GBA mutation carriers ( 31755958)
  • Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
  • Triglyceride levels ( 29083408)
  • Triglycerides ( 30275531)
Interacting Genes 63 interacting genes: ADGRE5 ALDOA ANGPTL6 AP1G2 ATP5MC2 B3GALT6 BAG6 C1GALT1 CBX5 CCT5 CENPBD1 CHD4 CTSB CTSH DCP1B DNASE2 DPP7 DXO EXOSC1 EXOSC10 EXOSC6 EXOSC8 FADS1 FBXO7 GLMP HEATR1 HERC2P4 HNRNPA1 KATNB1 LDHA LEPR LGALS3BP LINC01541 LSM4 MAN2C1 MFSD5 MTCH2 MTREX NDUFA13 NDUFB10 NDUFB9 PABPC4 PLEKHG2 POLD2 PPP2CA PRADC1 PSMB5 RBMX RNF187 SDHB SKIV2L SMARCD2 SNHG1 SPATA20 SRRM2 STAM2 TMEM50A UPF1 UPF2 UPF3B VWA5B2 WAPL ZFP36 36 interacting genes: A2M ACAN ADAMTSL4 ANXA2 ANXA7 APOE APP BAG6 BGLAP CDKN1A CST3 CST7 CSTA CSTB CTSD FAM118B HNRNPD HSPB2 IGF1 INS MARCKS MTDH PARP1 PLAU REN RGS2 S100A10 SERPINB13 SLPI SPHK1 SPINT2 SPRY2 SRPX2 STK11 UBQLN4 XRN1
Entrez ID 54464 1508
HPRD ID 10470 00287
Ensembl ID ENSG00000114127 ENSG00000164733
Uniprot IDs Q8IZH2 A0A024R374 B4DMY4 P07858 Q5HYG5
PDB IDs 1CSB 1GMY 1HUC 1PBH 2IPP 2PBH 3AI8 3CBJ 3CBK 3K9M 3PBH 5MBL 5MBM 6AY2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?