POLD2 and POLDIP2

Number of citations of the paper that reports this interaction (PubMedID 12522211)
35

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		POLD2	POLDIP2
Description		DNA polymerase delta 2, accessory subunit	DNA polymerase delta interacting protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Zeta DNA Polymerase Complex DNA Polymerase Complex Delta DNA Polymerase Complex	Nucleus Mitochondrion Mitochondrial Nucleoid
	Molecular Function	DNA Binding Protein Binding	DNA Binding Protein Binding
	Biological Process	Telomere Maintenance DNA Replication DNA Strand Elongation Involved In DNA Replication Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair, DNA Incision, 5'-to Lesion Nucleotide-excision Repair, DNA Gap Filling Mismatch Repair Translesion Synthesis Telomere Maintenance Via Semi-conservative Replication Nucleotide-excision Repair, DNA Incision DNA Damage Response, Detection Of DNA Damage DNA Biosynthetic Process	Negative Regulation Of Macroautophagy Positive Regulation Of Mitotic Cell Cycle Mitochondrion Morphogenesis
Pathways		Recognition of DNA damage by PCNA-containing replication complex Polymerase switching on the C-strand of the telomere Processive synthesis on the C-strand of the telomere Telomere C-strand (Lagging Strand) Synthesis Removal of the Flap Intermediate from the C-strand Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) PCNA-Dependent Long Patch Base Excision Repair Termination of translesion DNA synthesis HDR through Homologous Recombination (HRR) Gap-filling DNA repair synthesis and ligation in GG-NER Dual Incision in GG-NER Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand
Drugs
Diseases
GWAS			Blood protein levels ( 29875488) Osteoprotegerin levels ( 25080503)
Interacting Genes		18 interacting genes: CCHCR1 CDK2 CDKN1A EP300 ERBB2 KCTD13 LSM6 PCNA POLD1 POLD3 POLD4 POLDIP2 POLDIP3 POLH SOX12 WRN WRNIP1 XRN1	17 interacting genes: ALAS1 APP ASCC2 CPE FBXO7 HDAC6 MAD2L2 MTUS2 PCNA PDPK1 POLD2 POLN PTEN REV1 SELENBP1 TAB1 TMEM97
Entrez ID		5425	26073
HPRD ID		15982	17874
Ensembl ID		ENSG00000106628	ENSG00000004142
Uniprot IDs		A0A087WWF6 P49005	B4DEM9 Q9Y2S7
PDB IDs		3E0J
Enriched GO Terms of Interacting Partners?
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