PRRX1 and MAFG

Number of citations of the paper that reports this interaction (PubMedID 11036080)
12

Data Source:
HPRD (in vivo, in vitro)

		PRRX1	MAFG
Description		paired related homeobox 1	MAF bZIP transcription factor G
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm Cytosol	Cell Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Transcription Coactivator Activity HMG Box Domain Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Mesenchymal Cell Proliferation Embryonic Limb Morphogenesis Inner Ear Morphogenesis Middle Ear Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Neuron Fate Determination Embryonic Cranial Skeleton Morphogenesis Artery Morphogenesis Cartilage Development Roof Of Mouth Development Regulation Of Neuron Projection Regeneration Neuronal Stem Cell Population Maintenance	In Utero Embryonic Development Blood Coagulation Adult Behavior Regulation Of Cellular PH Regulation Of Cell Proliferation Regulation Of Epidermal Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Factors involved in megakaryocyte development and platelet production Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 28416822 29290336 29892015 22544366) Blood protein levels ( 29875488) Early onset atrial fibrillation ( 28460022) Emphysema imaging phenotypes ( 26030696) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Hip circumference adjusted for BMI ( 28552196 25673412) Intraocular pressure ( 29617998) Ischemic stroke (cardioembolic) ( 29531354) Macular thickness ( 30535121) Male-pattern baldness ( 29146897 28196072) Prevalent atrial fibrillation ( 28416818) Response to angiotensin II receptor blocker therapy ( 22566498) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		6 interacting genes: ATP1B1 GTF2I MAFF MAFG SOX10 SRF	25 interacting genes: ATF3 BACH2 BATF3 CHD3 CREBBP CYP2E1 DDIT3 GTF2A1L HIF1A HOXD12 MAF MAFF MAPK3 MED31 NFE2 NFE2L1 NFE2L2 NFIL3 PAX6 PIDD1 PPP1CA PRRX1 RBM48 SNRPN VIM
Entrez ID		5396	4097
HPRD ID		01337	03605
Ensembl ID		ENSG00000116132	ENSG00000197063
Uniprot IDs		P54821	A0A024R8X1 O15525
PDB IDs
Enriched GO Terms of Interacting Partners?
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