PLXNA1 and RND1

Number of citations of the paper that reports this interaction (PubMedID 11108845)
52

Data Source:
HPRD (in vitro)

		PLXNA1	RND1
Description		plexin A1	Rho family GTPase 1
Image		No pdb structure
GO Annotations	Cellular Component	Semaphorin Receptor Complex Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Cytoplasm Cytosol Plasma Membrane Adherens Junction Cell Cortex Actin Cytoskeleton Cytoplasmic Vesicle Cell Division Site Intracellular Membrane-bounded Organelle
	Molecular Function	Semaphorin Receptor Activity Signaling Receptor Activity	GTPase Activity Signaling Receptor Binding Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Negative Regulation Of Cell Adhesion Multicellular Organism Development Regulation Of Cell Shape Regulation Of Smooth Muscle Cell Migration Regulation Of Cell Migration Regulation Of GTPase Activity Positive Regulation Of Axonogenesis Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Neuron Projection Extension	Cytokinesis Actin Filament Organization Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Neuron Remodeling Regulation Of Cell Migration Establishment Or Maintenance Of Actin Cytoskeleton Polarity Regulation Of Actin Cytoskeleton Organization Actin Filament Bundle Assembly
Pathways		Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling CRMPs in Sema3A signaling Other semaphorin interactions	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Sema4D mediated inhibition of cell attachment and migration Sema4D induced cell migration and growth-cone collapse
Drugs
Diseases
GWAS		Alcoholic chronic pancreatitis ( 28754779) Blood protein levels ( 30072576 29875488) Systolic blood pressure ( 31469255) Weight ( 28552196) Whole-brain volume ( 21116278)	Bipolar disorder ( 21926972)
Interacting Genes		9 interacting genes: AKT1 FES L1CAM NRP1 NRP2 PLXNB1 RHOD RND1 SEMA6D	12 interacting genes: ARHGAP5 CREB3L2 FRS2 FRS3 GRB7 ID3 PDE6D PLXNA1 PLXNB1 PLXNB2 UBXN11 ZNF212
Entrez ID		5361	27289
HPRD ID		11868	12357
Ensembl ID		ENSG00000114554	ENSG00000172602
Uniprot IDs		Q9UIW2	Q92730
PDB IDs			2CLS 2REX 3Q3J
Enriched GO Terms of Interacting Partners?
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