PLN and SLN

Number of citations of the paper that reports this interaction (PubMedID 12692302)
41

Data Source:
HPRD (in vivo)

		PLN	SLN
Description		phospholamban	sarcolipin
Image
GO Annotations	Cellular Component	Cell Mitochondrion Endoplasmic Reticulum Membrane Mitochondrial Membrane Vesicle Sarcoplasmic Reticulum Membrane Perinuclear Region Of Cytoplasm Calcium Ion-transporting ATPase Complex	Integral Component Of Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane
	Molecular Function	Enzyme Inhibitor Activity Calcium Channel Regulator Activity Protein Binding ATPase Inhibitor Activity Identical Protein Binding Protein Homodimerization Activity ATPase Binding	Enzyme Inhibitor Activity Protein Binding ATPase Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Calcium Ion Transport Notch Signaling Pathway Blood Circulation Regulation Of Heart Contraction Response To Zinc Ion Negative Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of ATPase Activity Response To Insulin Response To Testosterone Negative Regulation Of Catalytic Activity Cardiac Muscle Tissue Development Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Calcium Ion Transport Negative Regulation Of Calcium Ion Transport Relaxation Of Cardiac Muscle Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Cell Contraction Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Regulation Of Cardiac Muscle Cell Membrane Potential Regulation Of The Force Of Heart Contraction By Cardiac Conduction Negative Regulation Of Calcium Ion Import Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Calcium Ion Binding Regulation Of Calcium-transporting ATPase Activity Negative Regulation Of Calcium-transporting ATPase Activity Regulation Of Relaxation Of Cardiac Muscle Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum	Calcium Ion Transport Negative Regulation Of Catalytic Activity Negative Regulation Of Protein Complex Disassembly Regulation Of Calcium Ion Transport Sarcoplasmic Reticulum Calcium Ion Transport Negative Regulation Of Calcium Ion Import Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Relaxation Of Muscle Negative Regulation Of Calcium Ion Binding Positive Regulation Of Protein Depolymerization Regulation Of Calcium-transporting ATPase Activity
Pathways		Ion homeostasis Ion transport by P-type ATPases	Ion homeostasis Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 30061737) Cardiac structure and function ( 19584346) QRS complex (Sokolow-Lyon) ( 27659466) QRS duration ( 27577874 27659466) QT interval ( 23166209 24952745 19305408 19305409 19587794) Resting heart rate ( 27798624)
Interacting Genes		14 interacting genes: ATP2A1 ATP2A2 BCL2L13 CREB3 CREB3L1 DMPK DVL3 EDA LDLRAD1 PPP1R3A PRKACA S100A1 SLN TMEM79	8 interacting genes: ATP2A1 DDX10 KASH5 LMNA PLN PTPN11 SYNE4 TMEM79
Entrez ID		5350	6588
HPRD ID		01395	03729
Ensembl ID		ENSG00000198523	ENSG00000170290
Uniprot IDs		P26678 Q5R352	A0A158RFT9 O00631
PDB IDs		1K9N 1KCH 1PLN 1PLP 1PSL 1ZLL 2HYN	1JDM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?