NUP54 and IFT20

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NUP54	IFT20
Description		nucleoporin 54	intraflagellar transport 20
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Membrane Host Cell Nuclear Pore Central Transport Channel	Golgi Membrane Photoreceptor Outer Segment Golgi Apparatus Cis-Golgi Network Centrosome Centriole Microvillus Cilium Intraciliary Transport Particle B Motile Cilium Photoreceptor Connecting Cilium Stereocilium Dendrite Terminus Ciliary Tip Ciliary Base Kinociliary Basal Body
	Molecular Function	Protein Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein-containing Complex Binding	Opsin Binding Protein Binding Rab GTPase Binding
	Biological Process	Regulation Of Glycolytic Process MRNA Export From Nucleus TRNA Export From Nucleus Protein Targeting NLS-bearing Protein Import Into Nucleus Nuclear Pore Organization Viral Process Protein Sumoylation Viral Transcription Protein Localization To Nuclear Inner Membrane Regulation Of Protein Import Into Nucleus Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat	Establishment Of Planar Polarity Kidney Development Smoothened Signaling Pathway Spermatogenesis Visual Learning Protein Localization To Golgi Apparatus Intraciliary Transport Involved In Cilium Assembly Photoreceptor Cell Outer Segment Organization Opsin Transport Intraciliary Transport Establishment Of Epithelial Cell Apical/basal Polarity Centrosome Localization Cardiac Muscle Cell Differentiation Inner Ear Receptor Cell Stereocilium Organization Cilium Assembly Regulation Of Canonical Wnt Signaling Pathway Neural Precursor Cell Proliferation Protein Localization To Cilium Protein Localization To Plasma Membrane Cochlea Development Regulation Of Cilium Assembly Regulation Of Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Regulation Of Autophagosome Assembly
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events Postmitotic nuclear pore complex (NPC) reformation	Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Hippocampal volume ( 29274321)	Osteoprotegerin levels ( 25080503)
Interacting Genes		17 interacting genes: AP2B1 APC CCDC85B DGCR6 GOLIM4 HAUS1 HGS IFT20 KPNA1 KPNB1 KRT15 NR3C1 NUP62 NUTF2 SEPTIN11 SSR1 THAP6	27 interacting genes: ABI2 BLOC1S6 CROCCP2 DISC1 DTNBP1 EMILIN1 EXOC7 FBF1 FSD2 GOLGA2 HAUS1 HTT IFT57 KIF3B KPNA2 KRT13 KXD1 NDC80 NUP54 NUP62 PSMA1 PTPN12 TREX1 USHBP1 WASF1 WASHC3 ZDHHC17
Entrez ID		53371	90410
HPRD ID		06352	17137
Ensembl ID		ENSG00000138750	ENSG00000109083
Uniprot IDs		Q7Z3B4	A0A024QZ08 A0A087X2B4 Q8IY31
PDB IDs		4JNU 4JNV 4JO7 4JO9 5IJN 5IJO
Enriched GO Terms of Interacting Partners?
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