PI4KA and TNNT1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		PI4KA	TNNT1
Description		phosphatidylinositol 4-kinase alpha	troponin T1, slow skeletal type
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Viral Replication Complex Golgi-associated Vesicle Membrane Extracellular Exosome	Cytosol Troponin Complex
	Molecular Function	1-phosphatidylinositol 4-kinase Activity Protein Binding ATP Binding Kinase Activity Cadherin Binding Phosphatidylinositol Kinase Activity	Calcium Ion Binding Protein Binding Tropomyosin Binding Calcium-dependent ATPase Activity Troponin T Binding
	Biological Process	Phosphatidylinositol Biosynthetic Process Signal Transduction Phosphorylation Viral RNA Genome Replication Multi-organism Membrane Organization Viral Replication Complex Formation And Maintenance Phosphatidylinositol Phosphorylation Phosphatidylinositol-mediated Signaling	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction Cardiac Muscle Contraction
Pathways		Synthesis of PIPs at the ER membrane Synthesis of PIPs at the Golgi membrane	Striated Muscle Contraction
Drugs
Diseases			Nemaline myopathy
GWAS		Fulminant type 1 diabetes ( 30552108) Metabolite levels ( 23823483)	Height ( 31562340)
Interacting Genes		10 interacting genes: C8orf33 CD4 CD7 LCK MRPL44 MTNR1B PITPNA SNX9 STRN4 TNNT1	61 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT40 LARP1 LDOC1 MARS1 MORF4L1 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TPM1 TPM3 TRA2A TRIM63 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768
Entrez ID		5297	7138
HPRD ID		08972	01841
Ensembl ID		ENSG00000241973	ENSG00000105048
Uniprot IDs		B4DYG5 P42356 Q4LE69	P13805
PDB IDs		6BQ1
Enriched GO Terms of Interacting Partners?
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