PIGR and CD79A

Number of citations of the paper that reports this interaction (PubMedID 12186846)
5

Data Source:
HPRD (in vivo)

		PIGR	CD79A
Description		polymeric immunoglobulin receptor	CD79a molecule
Image
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Azurophil Granule Membrane Receptor Complex Extracellular Exosome	Multivesicular Body Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane B Cell Receptor Complex Membrane Raft
	Molecular Function	Polymeric Immunoglobulin Receptor Activity	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Epidermal Growth Factor Receptor Signaling Pathway Fc Receptor Signaling Pathway Receptor Clustering Neutrophil Degranulation	Adaptive Immune Response B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway
Pathways		Neutrophil degranulation	CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Blood protein levels ( 30072576 29875488) Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Inflammatory bowel disease ( 23128233) Metabolite levels ( 23823483) Precuneus cortex volume ( 31530798)
Interacting Genes		4 interacting genes: AP1M1 CCL5 CD79A RAB3B	17 interacting genes: BLK BLNK CD19 CD5 CD79B FANCA FATE1 FCAR FYN HCLS1 IGHM JCHAIN LCK LYN PIGR PTPN6 SYK
Entrez ID		5284	973
HPRD ID		01436	00203
Ensembl ID		ENSG00000162896	ENSG00000105369
Uniprot IDs		P01833	P11912
PDB IDs		1XED 2OCW 3CHN 3CM9 5D4K	1CV9
Enriched GO Terms of Interacting Partners?
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