SYT17 and CHMP4A

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)
HPRD (two hybrid)

		SYT17	CHMP4A
Description		synaptotagmin 17	charged multivesicular body protein 4A
Image
GO Annotations	Cellular Component	Trans-Golgi Network Plasma Membrane Exocytic Vesicle	ESCRT III Complex Cell Nucleus Cytoplasm Endosome Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Coat Midbody Cytoplasmic Vesicle Membrane Late Endosome Membrane
	Molecular Function	SNARE Binding Phosphatidylserine Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Clathrin Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity ATPase Binding
	Biological Process	Regulation Of Dopamine Secretion Vesicle-mediated Transport Calcium Ion Regulated Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Cellular Response To Calcium Ion Positive Regulation Of Dendrite Extension	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Vesicle Budding From Membrane Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Membrane Invagination Endosomal Transport Macroautophagy Viral Life Cycle Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Protein Polymerization Midbody Abscission Plasma Membrane Tubulation Negative Regulation Of Neuron Death Negative Regulation Of Autophagosome Assembly
Pathways			Budding and maturation of HIV virion Macroautophagy Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy Sealing of the nuclear envelope (NE) by ESCRT-III
Drugs
Diseases
GWAS		Alcohol dependence ( 21876473) Parkinson's disease ( 27182965) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		17 interacting genes: APP APTX CCDC85B CEP63 CEP70 CHMP4A FAM9B GMCL1 IKZF1 MEOX1 MEOX2 NIF3L1 NINL RUNDC3A SSX2IP TRAF2 TSC22D4	12 interacting genes: CC2D1A CDK13 CHMP3 CHMP4B CHMP4C CHMP5 CHMP6 PDCD6IP STAMBP SYT17 TTC19 VPS4A
Entrez ID		51760	29082
HPRD ID		17425	16597
Ensembl ID		ENSG00000103528	ENSG00000254505
Uniprot IDs		H3BN78 H3BRH9 Q9BSW7	Q9BY43
PDB IDs		2ENP	3C3O 5MK1
Enriched GO Terms of Interacting Partners?
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