DYNC2LI1 and DYNC2H1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo, in vitro)

		DYNC2LI1	DYNC2H1
Description		dynein cytoplasmic 2 light intermediate chain 1	dynein cytoplasmic 2 heavy chain 1
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GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoplasmic Dynein Complex Cytoplasmic Microtubule Cilium Axoneme Intraciliary Transport Particle Motile Cilium Ciliary Transition Zone Ciliary Basal Body Apical Part Of Cell Ciliary Tip	Golgi Apparatus Cytoplasmic Dynein Complex Microtubule Plasma Membrane Cilium Axoneme Dynein Complex Motile Cilium Apical Part Of Cell Extracellular Exosome Ciliary Tip
	Molecular Function	Protein Binding ATP-dependent Microtubule Motor Activity, Minus-end-directed Dynein Heavy Chain Binding	Motor Activity ATP Binding ATP-dependent Microtubule Motor Activity, Minus-end-directed Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Determination Of Left/right Symmetry Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Regulation Of Cilium Assembly	Microtubule-based Movement Golgi Organization Determination Of Left/right Symmetry Dorsal/ventral Pattern Formation Protein Processing Spinal Cord Motor Neuron Differentiation Embryonic Limb Morphogenesis Forebrain Development Intraciliary Retrograde Transport Intraciliary Transport Involved In Cilium Assembly Positive Regulation Of Smoothened Signaling Pathway Cilium Assembly Coronary Vasculature Development Protein Localization To Cilium Non-motile Cilium Assembly
Pathways		Intraflagellar transport	Hedgehog 'off' state Intraflagellar transport
Drugs
Diseases			Short rib-polydactyly syndrome Asphyxiating thoracic dystrophy; Jeune syndrome
GWAS		Coronary artery disease ( 29212778) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Coronary artery disease ( 30104761) Diisocyanate-induced asthma ( 25918132) Response to lurasidone in schizophrenia ( 29730043) Small-cell lung cancer (survival) ( 21118971) Spine bone mineral density and alcohol drinking ( 28012008) Toenail selenium levels ( 25343990) Tuberculosis ( 24057671)
Interacting Genes		1 interacting genes: DYNC2H1	3 interacting genes: DYNC2LI1 MTNR1B PAXIP1
Entrez ID		51626	79659
HPRD ID		13116	10344
Ensembl ID		ENSG00000138036	ENSG00000187240
Uniprot IDs		Q8TCX1	Q8NCM8
PDB IDs		6RLB 6SC2	4RH7
Enriched GO Terms of Interacting Partners?
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