DPH5 and RUSC1

		DPH5	RUSC1
Description		diphthamide biosynthesis 5	RUN and SH3 domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytosol	Nucleus Early Endosome Golgi Apparatus Cytosol Microtubule Postsynaptic Density Microtubule Cytoskeleton Cell Junction Cytoplasmic Vesicle
	Molecular Function	Diphthine Synthase Activity	Actin Binding SH3/SH2 Adaptor Activity Protein Binding
	Biological Process	Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Methylation	Protein Polyubiquitination Positive Regulation Of Signal Transduction
Pathways		Synthesis of diphthamide-EEF2
Drugs		S-adenosyl-L-homocysteine
Diseases
GWAS		Irritable bowel syndrome ( 29673008) QT interval (drug interaction) ( 23459443)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908)
Interacting Genes		3 interacting genes: MFSD14A RUSC1 SLC30A7	9 interacting genes: APP DPH5 DVL2 FAM9B NTRK1 PNMA1 RBPMS STUB1 WWP2
Entrez ID		51611	23623
HPRD ID		13037	10206
Ensembl ID		ENSG00000117543	ENSG00000160753
Uniprot IDs		B3KWP1 Q9H2P9	B4DQB8 Q9BVN2
PDB IDs			4GIW
Enriched GO Terms of Interacting Partners?
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