MED15 and ATP5F1C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MED15	ATP5F1C
Description		mediator complex subunit 15	ATP synthase F1 subunit gamma
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Membrane Mediator Complex	Mitochondrial Proton-transporting ATP Synthase Complex, Catalytic Core F(1) Mitochondrion Mitochondrial Inner Membrane Mitochondrial Proton-transporting ATP Synthase Complex Mitochondrial Matrix Membrane
	Molecular Function	Transcription Coregulator Activity Protein Binding	RNA Binding ATPase Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Stem Cell Population Maintenance	Oxidative Phosphorylation ATP Biosynthetic Process ATP Synthesis Coupled Proton Transport Cristae Formation Mitochondrial ATP Synthesis Coupled Proton Transport
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation	Formation of ATP by chemiosmotic coupling Cristae formation
Drugs			Quercetin 1-ACETYL-2-CARBOXYPIPERIDINE AUROVERTIN B PICEATANNOL N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
Diseases
GWAS		Lung function (FEV1/FVC) ( 30061609)
Interacting Genes		12 interacting genes: ATP5F1C ATXN1 CTDP1 FHL3 MED25 MLLT6 PLSCR1 RELA SMAD2 SMAD3 TRIM11 UBC	25 interacting genes: APP ATP5F1A ATP5F1B CA12 CCND3 CCT7 CHMP2B DPP3 EGFR ELOF1 FBXO7 GDPD2 ITIH2 MED15 MPP1 NDUFB3 NGEF PAWR PJA1 PNO1 POLA2 PTEN PTN SERPINA1 ZNF337
Entrez ID		51586	509
HPRD ID		12117	00156
Ensembl ID		ENSG00000099917	ENSG00000165629
Uniprot IDs		B7Z2H7 G3V1P5 Q6PKB8 Q96RN5	B4DL14 P36542 Q8TAS0
PDB IDs		2GUT
Enriched GO Terms of Interacting Partners?
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