RAB14 and TLR4

RAB14

TLR4

Description RAB14, member RAS oncogene family toll like receptor 4
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
  • Blood protein levels ( 29875488 28240269)
  • BMI (adjusted for smoking behaviour) ( 28443625)
  • BMI in non-smokers ( 28443625)
  • Body mass index ( 25673413 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index (joint analysis main effects and smoking interaction) ( 28443625)
  • Body mass index in physically active individuals ( 28448500)
  • Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007)
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
  • Experiencing mood swings ( 29500382)
  • Feeling fed-up ( 29500382)
  • Feeling guilty ( 29500382)
  • Impulsivity (motor) ( 30718321)
  • Irritable mood ( 29500382)
  • Metabolite levels ( 23823483)
  • Neurociticism ( 29500382)
  • Neuroticism ( 29255261)
  • Obesity-related traits ( 23251661)
  • Osteoarthritis biomarkers ( 25057126)
  • Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) ( 24823311)
  • Prostate-specific antigen levels ( 28139693)
  • Voxel-wise structural brain imaging measurements in Alzheimer’s disease ( 30584014)
Interacting Genes 16 interacting genes: APP ARHGEF17 CHM EXOC5 FGA GSN NR5A1 OCRL OPTN RAB11FIP5 RBSN RUFY1 SMURF2 TLR4 TNC XRN2 26 interacting genes: BCL10 BTK CD14 CNPY4 DEFB4A HMGB1 HSP90B1 IRAK1 IRAK2 LY96 MAPK8IP3 MYD88 NOX4 RAB14 RIPK2 RNF216 SERTAD1 SIGIRR SMAD3 SYK TICAM2 TIRAP TLR1 TLR5 TOLLIP UBQLN1
Entrez ID 51552 7099
HPRD ID 06693 04325
Ensembl ID ENSG00000119396 ENSG00000136869
Uniprot IDs A0A024R845 P61106 O00206
PDB IDs 1Z0F 4D0G 4DRZ 2Z62 2Z63 2Z65 2Z66 3FXI 3UL7 3UL8 3UL9 3ULA 4G8A 5NAM 5NAO
Enriched GO Terms of Interacting Partners?
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