NCKIPSD and DMRTB1

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NCKIPSD	DMRTB1
Description		NCK interacting protein with SH3 domain	DMRT like family B with proline rich C-terminal 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament COP9 Signalosome	Nuclear Chromatin Nucleus
	Molecular Function	Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Cytoskeleton Organization Positive Regulation Of Neuron Projection Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis	Regulation Of Transcription By RNA Polymerase II
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Anorexia nervosa ( 31308545) Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Parkinson's disease ( 28892059) Ulcerative colitis ( 28067908)	Cerebrospinal fluid AB1-42 levels ( 28247064) Response to statin therapy ( 20339536)
Interacting Genes		20 interacting genes: ARHGEF7 BAIAP2 DIAPH2 DIAPH3 DLG4 DMRTB1 FASLG GRB2 HSPB1 ITGB1 KHDRBS1 MAPK3 NCK1 NCK2 PSMD9 SORBS3 STAC WAS WASL YWHAG	30 interacting genes: C1orf94 CCND3 CDKN2D CTBP1 CTBP2 EWSR1 EXOSC1 EXOSC5 EYA2 FXR2 HNRNPUL1 IL16 LENG8 NCKIPSD NEDD9 NIF3L1 PARD6G PEF1 PKP2 PRMT2 QKI RBFOX1 RBFOX2 RBM14 RBPMS RPA2 SLAIN1 SORBS3 TSG101 VASP
Entrez ID		51517	63948
HPRD ID		09450	16828
Ensembl ID		ENSG00000213672	ENSG00000143006
Uniprot IDs		Q9NZQ3	I6L9A0 Q96MA1
PDB IDs		6DEC 6DED 6DEE
Enriched GO Terms of Interacting Partners?
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