FAM8A1 and GMPR

		FAM8A1	GMPR
Description		family with sequence similarity 8 member A1	guanosine monophosphate reductase
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Cytosol GMP Reductase Complex
	Molecular Function		GMP Reductase Activity Metal Ion Binding
	Biological Process		Purine Nucleobase Metabolic Process Response To Cold Purine Ribonucleotide Interconversion Purine-containing Compound Salvage Oxidation-reduction Process
Pathways			Purine salvage
Drugs			Guanosine-5'-Monophosphate
Diseases
GWAS		Idiopathic intracranial hypertension ( 29608535)	Blood metabolite levels ( 24816252) Gambling ( 22780124) General cognitive ability ( 29844566) Hemoglobin concentration ( 27863252) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) LDL cholesterol ( 20864672) Major depressive disorder ( 23377640) Mean corpuscular hemoglobin ( 29403010 27863252) Mean corpuscular hemoglobin concentration ( 29403010 27863252) Mean corpuscular volume ( 29403010 27863252) QT interval ( 24952745) Response to statins (LDL cholesterol change) ( 22331829) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		5 interacting genes: ATP13A2 CD83 GMPR H4C13 SLC17A4	2 interacting genes: FAM8A1 RIPK1
Entrez ID		51439	2766
HPRD ID		13316	00754
Ensembl ID		ENSG00000137414	ENSG00000137198
Uniprot IDs		A0A024R006 Q9UBU6	P36959
PDB IDs			2BLE 2BWG
Enriched GO Terms of Interacting Partners?
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