CDK18 and SEC23A

Number of citations of the paper that reports this interaction (PubMedID 16091426)
47

Data Source:
HPRD (in vivo, two hybrid)

		CDK18	SEC23A
Description		cyclin dependent kinase 18	Sec23 homolog A, COPII coat complex component
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Nucleus Cytoplasm	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane Extrinsic Component Of Membrane COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	GTPase Activator Activity Protein Binding Zinc Ion Binding
	Biological Process	Protein Phosphorylation Regulation Of Cell Cycle	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Positive Regulation Of GTPase Activity COPII Vesicle Coating Protein Localization To Plasma Membrane Cargo Loading Into COPII-coated Vesicle
Pathways			Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases			Cranio-lenticulo-sutural dysplasia (CLSD); Boyadjiev-Jabs syndrome
GWAS		Coronary artery disease in type 1 diabetes ( 29695241)	Metabolite levels ( 23823483) Vitamin D levels ( 29343764)
Interacting Genes		18 interacting genes: APP CCDC102B CCDC85B CCNDBP1 CCNK GOLGA2 KIFC3 KRT31 KRT40 LZTS2 MIPOL1 MTUS2 PNMA1 SEC23A TRIM27 TRIM54 TSGA10 YWHAQ	11 interacting genes: CDK16 CDK18 DCTN1 GLRA2 MIA2 MIA3 NDRG1 SDCBP2 SEC16A SEC24B SEC24C
Entrez ID		5129	10484
HPRD ID		01354	06714
Ensembl ID		ENSG00000117266	ENSG00000100934
Uniprot IDs		A0A024R980 A0A024R996 Q07002 Q59G02	Q15436
PDB IDs			2NUP 2NUT 2YRC 2YRD 3EFO 3EG9 3EGD 3EGX 5KYN 5KYU 5KYW 5KYX 5KYY 5VNE 5VNF 5VNG 5VNH 5VNI 5VNJ 5VNK 5VNL 5VNM 5VNN 5VNO
Enriched GO Terms of Interacting Partners?
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