CDK16 and APPBP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CDK16	APPBP2
Description		cyclin dependent kinase 16	amyloid beta precursor protein binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Synaptic Vesicle Microtubule Cytoskeleton Cell Junction Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Neuron Projection	Nucleus Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane
	Molecular Function	Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Microtubule Motor Activity Protein Binding
	Biological Process	Protein Phosphorylation Exocytosis Spermatogenesis Growth Hormone Secretion Neuron Projection Development Regulation Of Cell Cycle Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus	Intracellular Protein Transport Intracellular Transport
Pathways
Drugs		(2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}
Diseases
GWAS			Waist-hip ratio ( 28552196)
Interacting Genes		17 interacting genes: APP APPBP2 ATRIP BAG6 CDK5 CDK5R1 PJA1 PRKACA S100A10 SEC23A SIRPA YWHAE YWHAG YWHAH YWHAQ YWHAZ ZBTB14	81 interacting genes: - AHCY AIM2 AK3 ANKRD10 APP AR ARMCX5 C1orf50 C6orf226 CALM3 CCDC85C CCNL1 CDK16 CHMP5 CIBAR1 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CTC1 CYBA DCD DHRS2 DPEP1 EID3 ERO1A FAM107A FSTL1 FXYD7 GALNT3 GCSAM GP9 GSTP1 H2AC15 HIPK4 HSPA4 KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MFSD3 MLLT3 MUL1 NFYA NPRL3 PCSK5 PI4KAP2 PPP1R8 PRKAA2 PRKACB PYROXD2 RASSF5 RNF128 RNF34 RRS1 SELENOI SELENOV SLC22A6 SLC25A23 SNX5 ST8SIA5 SYNRG SYT11 TAF11 TAFA4 TBL3 TCF25 UBE2R2 UGGT2 WAS WDR24 WNT5B ZC3H10 ZCCHC12 ZNF747
Entrez ID		5127	10513
HPRD ID		02409	05616
Ensembl ID		ENSG00000102225	ENSG00000062725
Uniprot IDs		A0A024R183 A0A140VK97 Q00536 Q9BRL4	A0A024QZ47 Q92624
PDB IDs		3MTL 5G6V
Enriched GO Terms of Interacting Partners?
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