LUZP4 and FOSL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LUZP4	FOSL2
Description		leucine zipper protein 4	FOS like 2, AP-1 transcription factor subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nuclear Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Binding Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	MRNA Transport	Keratinocyte Development Regulation Of Transcription By RNA Polymerase II Cell Death Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Fibroblast Proliferation
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29679657) Allergic rhinitis ( 30013184) Blond vs. brown/black hair color ( 30531825) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Soluble interleukin-2 receptor subunit alpha ( 26293465) Systolic blood pressure ( 28135244 30578418) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Type 1 diabetes ( 21980299)
Interacting Genes		14 interacting genes: APPBP2 CLK2 DDX39B EMD FOS FOSL2 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 NXF1 RCOR3 SRPK2 TLK1	14 interacting genes: CREB5 DDIT3 DNAJA3 DNMT3L EP300 FHL3 GMCL1 GOPC JUN JUNB JUND LUZP4 SRA1 TRAF1
Entrez ID		51213	2355
HPRD ID		06589	03343
Ensembl ID		ENSG00000102021	ENSG00000075426
Uniprot IDs		Q9P127	P15408 Q9H5M2
PDB IDs
Enriched GO Terms of Interacting Partners?
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