KMT5B and SMARCD1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		KMT5B	SMARCD1
Description		lysine methyltransferase 5B	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome, Centromeric Region Nucleus Nucleoplasm	Nucleoplasm SWI/SNF Complex Intracellular Membrane-bounded Organelle NpBAF Complex NBAF Complex
	Molecular Function	Chromatin Binding Histone-lysine N-methyltransferase Activity Histone Methyltransferase Activity (H4-K20 Specific) Metal Ion Binding S-adenosyl-L-methionine Binding	Chromatin Binding Transcription Coactivator Activity Signaling Receptor Binding Protein Binding Molecular Adaptor Activity
	Biological Process	DNA Repair Muscle Organ Development Histone H4-K20 Trimethylation Positive Regulation Of Isotype Switching Positive Regulation Of Double-strand Break Repair Via Nonhomologous End Joining	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Chromatin-mediated Maintenance Of Transcription Cellular Response To Fatty Acid
Pathways		PKMTs methylate histone lysines	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Urate levels ( 31578528)	Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)
Interacting Genes		3 interacting genes: ESR1 H4C1 SMARCD1	50 interacting genes: ANKS1A ANP32B APOA5 AR C4BPA CALCOCO2 CCDC85B CDC5L CDX2 CHFR CHN2 CLNK CORO1A EGFL7 ESR1 FBXO7 FEZ1 FOS FUS GATA1 GCC1 HNRNPC HSPB1 IGKC JUN KDM1A KLF1 KMT5B KRT15 KRT18 LDOC1 MED4 MTNR1B NME1 NONO NR1H4 NR3C1 NUCB2 PAICS PCBD1 PGR PRDX1 PRMT6 RIF1 RPS29 TNIP2 TP53 USHBP1 VPS37B YWHAG
Entrez ID		51111	6602
HPRD ID		11616	03438
Ensembl ID		ENSG00000110066	ENSG00000066117
Uniprot IDs		B7WNX0 B7Z5N2 Q4FZB7	Q96GM5
PDB IDs		3S8P 5CPR 5WBV
Enriched GO Terms of Interacting Partners?
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