CRYL1 and ABCC6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CRYL1	ABCC6
Description		crystallin lambda 1	ATP binding cassette subfamily C member 6
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GO Annotations	Cellular Component	Cytosol Extracellular Exosome	Nucleoplasm Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane
	Molecular Function	3-hydroxyacyl-CoA Dehydrogenase Activity Protein Homodimerization Activity L-gulonate 3-dehydrogenase Activity NAD+ Binding	Transporter Activity ATP Binding ATPase Activity ATPase Activity, Coupled To Transmembrane Movement Of Substances
	Biological Process	Fatty Acid Metabolic Process Glucuronate Catabolic Process To Xylulose 5-phosphate Oxidation-reduction Process	Visual Perception Response To Drug Transmembrane Transport
Pathways		Formation of xylulose-5-phosphate	ABC-family proteins mediated transport Defective ABCC6 causes pseudoxanthoma elasticum (PXE)
Drugs			ATP
Diseases			Pseudoxanthoma elasticum, including: Pseudoxanthoma elasticum (PXE); Pseudoxanthoma elasticum-like disorder with multiple coagulation factor deficiency
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065) Obesity-related traits ( 23251661)	Multiple myeloma (survival) ( 26198393)
Interacting Genes		1 interacting genes: ABCC6	5 interacting genes: A1BG AK2 CRYL1 FURIN NR4A1
Entrez ID		51084	368
HPRD ID		16762	04453
Ensembl ID		ENSG00000165475	ENSG00000091262
Uniprot IDs		Q9Y2S2 V9HWG2	O95255
PDB IDs		3F3S	6BZR 6BZS
Enriched GO Terms of Interacting Partners?
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