PCBP1 and PRPF3

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		PCBP1	PRPF3
Description		poly(rC) binding protein 1	pre-mRNA processing factor 3
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding	RNA Binding Protein Binding Identical Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Metabolic Process Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways		mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	mRNA Splicing - Major Pathway
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)	Blood protein levels ( 28240269) Chronotype ( 27494321) Low density lipoprotein cholesterol levels ( 30498476) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Platelet count ( 27863252) Plateletcrit ( 27863252)
Interacting Genes		42 interacting genes: ANP32A APP CAV3 CELF2 CELF3 ERG EWSR1 FTH1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL LMNA MATR3 MOGS NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM42 SNRPA SRPK2 SRSF3 TCERG1 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830	31 interacting genes: BRCA1 CASK CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GPRASP2 GTPBP3 MAPRE1 MID2 NAV2 NKAP PCBP1 PHC2 PRPF31 PSMD3 RBM39 SART3 SNIP1 SNRNP200 TRIM39 U2AF2 USP4 WBP4 ZBTB8A ZCCHC10 ZGPAT
Entrez ID		5093	9129
HPRD ID		03128	07389
Ensembl ID		ENSG00000169564	ENSG00000117360
Uniprot IDs		Q15365 Q53SS8	O43395
PDB IDs		1WVN 1ZTG 3VKE	1X4Q 3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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