ORC2 and MCM2

  • Number of citations of the paper that reports this interaction (PubMedID 15232106)
  • 123
  • Data Source:
  • HPRD (in vivo, in vitro, two hybrid)

ORC2

MCM2

Description origin recognition complex subunit 2 minichromosome maintenance complex component 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Plasma parathyroid hormone levels ( 30134803)
  • Triptolide cytotoxicity ( 26121980)
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes 26 interacting genes: BCS1L CDC45 CDC5L CDC6 CDK2 CDT1 DBF4 EP300 H3-4 H4-16 KAT7 MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC3 ORC4 ORC5 ORC6 RPA1 RPA2 XRCC5 55 interacting genes: AKAP8 APP ATM ATR CCNB2 CCNC CDC45 CDC6 CDC7 CDK2 CDK4 CDK6 CDKN2A CDT1 CPSF1 CSNK2A1 DBF4 ELL EP300 ESCO2 FBXO7 GINS4 GNB5 GTF2B GTF2H1 H3-4 KAT7 MCM10 MCM3 MCM4 MCM5 MCM6 MCM7 MCPH1 MOB4 MPP3 ORC1 ORC2 ORC4 ORC5 ORC6 P2RX4 PHB PHC2 PLK1 RAD52 RPA1 RPA2 RPA3 RPS4X SIK1 TBP TCEA2 TERF1 TERF2IP
Entrez ID 4999 4171
HPRD ID 03112 00303
Ensembl ID ENSG00000115942 ENSG00000073111
Uniprot IDs A0A024R411 Q13416 P49736
PDB IDs 5C8H 5UJ8 5UJM 4UUZ 5BNV 5BNX 5BO0 5C3I 5JA4
Enriched GO Terms of Interacting Partners?
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