ODF2 and SVIL

Number of citations of the paper that reports this interaction (PubMedID 20309963)
26

Data Source:
BioGRID (two hybrid)

		ODF2	SVIL
Description		outer dense fiber of sperm tails 2	supervillin
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Outer Dense Fiber Nucleus Centrosome Centriole Cytosol Microtubule Sperm Flagellum Ciliary Transition Fiber Centriolar Subdistal Appendage	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere Invadopodium
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding Actin Filament Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Multicellular Organism Development Spermatid Development Protein Localization Regulation Of G2/M Transition Of Mitotic Cell Cycle Centriole-centriole Cohesion Cilium Organization Ciliary Basal Body-plasma Membrane Docking	Cytoskeleton Organization Skeletal Muscle Tissue Development Positive Regulation Of Cytokinesis
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Body mass index ( 26426971)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Bone fracture in osteoporosis ( 28580392) Estimated glomerular filtration rate ( 31152163) Lung function (FEV1/FVC) ( 28166213) Metabolite levels ( 23823483) Neurofibrillary tangles ( 25188341) Normalized brain volume ( 19010793) Platelet thrombus formation ( 22550155)
Interacting Genes		11 interacting genes: APP FBXO25 GOLGA2 LRRK1 MAP3K1 MARK4 ODF1 RAB8A SMURF1 SVIL ZDHHC17	36 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF14 KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG
Entrez ID		4957	6840
HPRD ID		03601	04992
Ensembl ID		ENSG00000136811	ENSG00000197321
Uniprot IDs		A0A024R8A4 A0A024R8A5 B3KSD5 B4DUU0 B4DX03 B4DX85 Q5BJF6	O95425 Q569J5
PDB IDs			2K6M 2K6N
Enriched GO Terms of Interacting Partners?
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