NUP98 and CHMP5

		NUP98	CHMP5
Description		nucleoporin 98 and 96 precursor	charged multivesicular body protein 5
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GO Annotations	Cellular Component	Kinetochore Nuclear Envelope Nuclear Pore Nucleoplasm Cytosol Nuclear Body Nuclear Pore Outer Ring Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Intracellular Membrane-bounded Organelle Host Cell Nuclear Pore Cytoplasmic Filaments Nuclear Pore Nuclear Basket Ribonucleoprotein Complex	Cell Nucleus Cytosol Endosome Membrane Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity RNA Binding MRNA Binding Transporter Activity Protein Binding Nuclear Localization Sequence Binding Serine-type Peptidase Activity Structural Constituent Of Nuclear Pore Promoter-specific Chromatin Binding	Protein Binding Cadherin Binding
	Biological Process	Posttranscriptional Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Regulation Of Glycolytic Process RNA Export From Nucleus MRNA Export From Nucleus TRNA Export From Nucleus Proteolysis Protein Import Into Nucleus Nucleocytoplasmic Transport Nuclear Pore Organization Viral Process Protein Sumoylation Viral Transcription Telomere Tethering At Nuclear Periphery Positive Regulation Of MRNA Splicing, Via Spliceosome Nuclear Pore Complex Assembly Regulation Of Gene Silencing By MiRNA Intracellular Transport Of Virus Regulation Of Cellular Response To Heat Positive Regulation Of Nucleic Acid-templated Transcription	Regulation Of Receptor Recycling Nucleus Organization Lysosome Organization Mitotic Metaphase Plate Congression Endosome To Lysosome Transport Regulation Of Centrosome Duplication Protein Transport Endosomal Transport Viral Life Cycle Multivesicular Body Assembly Viral Budding Midbody Abscission Cellular Response To Lipopolysaccharide Cellular Response To Muramyl Dipeptide Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly
Pathways			Budding and maturation of HIV virion Endosomal Sorting Complex Required For Transport (ESCRT)
Drugs
Diseases
GWAS		Metabolite levels (Dihydroxy docosatrienoic acid) ( 23934736)	Erectile dysfunction and prostate cancer treatment ( 20932654)
Interacting Genes		30 interacting genes: APC CBFA2T3 CHMP5 CREBBP CSNK2A1 CYFIP1 EP300 HBE1 HDAC1 IPO5 KCNQ1 KPNB1 MUC2 NUP133 NUP155 NUP214 NUP62 NUP88 NXF1 PSMD13 RAE1 RCC1 RNH1 RRM1 SEC13 SLC22A18AS TNPO1 TNPO2 TPR UTRN	17 interacting genes: APPBP2 CHMP1B CHMP4A CHMP4B GTF3A MITD1 NOD2 NUP98 PDCD10 RPL38 SMARCA4 STAMBP URGCP VPS4B VTA1 ZNF142 ZNF91
Entrez ID		4928	51510
HPRD ID		03012	15408
Ensembl ID		ENSG00000110713	ENSG00000086065
Uniprot IDs		P52948	Q9NZZ3
PDB IDs		1KO6 2Q5X 2Q5Y 3MMY 4OWR 5A9Q 6BZM	2LXM 3ULY 3UM0 3UM1 3UM2 4TXR
Enriched GO Terms of Interacting Partners?
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